ACIU
ACIU
AC Immune S.A.Income Statement
| Period | Revenue | Operating Expense | Net Income | Net Profit Margin | Earnings Per Share | EBITDA |
|---|---|---|---|---|---|---|
| Q4-2025 | $338K ▼ | $14.74M ▼ | $-14.26M ▲ | -4.22K% ▼ | $-0.14 ▲ | $-13.72M ▲ |
| Q3-2025 | $939K ▼ | $17.11M ▼ | $-15.86M ▲ | -1.69K% ▼ | $-0.16 ▲ | $-15.52M ▲ |
| Q2-2025 | $1.31M ▲ | $20.69M ▲ | $-21.19M ▼ | -1.62K% ▲ | $-0.21 ▼ | $-20.52M ▼ |
| Q1-2025 | $990K ▼ | $20.36M ▲ | $-19.03M ▼ | -1.92K% ▼ | $-0.19 ▼ | $-18.36M ▼ |
| Q4-2024 | $1.14M | $19.75M | $-15.8M | -1.39K% | $-0.14 | $-15.23M |
Balance Statement
| Period | Cash & Short-term | Total Assets | Total Liabilities | Total Equity |
|---|---|---|---|---|
| Q4-2025 | $91.52M ▼ | $154.43M ▼ | $109.49M ▲ | $44.93M ▼ |
| Q3-2025 | $108.47M ▼ | $171.61M ▼ | $109.16M ▼ | $62.44M ▼ |
| Q2-2025 | $127.14M ▼ | $190.22M ▼ | $115.48M ▼ | $74.74M ▼ |
| Q1-2025 | $145.61M ▼ | $211.08M ▼ | $116.28M ▼ | $94.8M ▼ |
| Q4-2024 | $165.49M | $230.91M | $118.64M | $112.27M |
Cash Flow Statement
| Period | Net Income | Cash From Operations | Cash From Investing | Cash From Financing | Net Change | Free Cash Flow |
|---|---|---|---|---|---|---|
| Q4-2025 | $-14.26M ▲ | $-16.45M ▲ | $15.94M ▼ | $-259.95K ▼ | $-828.4K ▼ | $-16.55M ▲ |
| Q3-2025 | $-15.86M ▲ | $-18.34M ▼ | $20.63M ▼ | $-254K ▼ | $2.02M ▼ | $-18.4M ▼ |
| Q2-2025 | $-21.19M ▼ | $-15.6M ▲ | $23.88M ▲ | $-247K ▲ | $5.76M ▲ | $-15.97M ▲ |
| Q1-2025 | $-19.03M ▼ | $-18.82M ▼ | $3.03M ▲ | $-258K ▼ | $-16.32M ▼ | $-19.18M ▼ |
| Q4-2024 | $-15.8M | $5.93M | $-3.83M | $-197K | $3.86M | $5.84M |
5-Year Trend Analysis
A comprehensive look at AC Immune S.A.'s financial evolution and strategic trajectory over the past five years.
Key strengths include a focused mission in high‑unmet‑need neurodegenerative diseases, proprietary technology platforms that underpin a diversified pipeline, and strong relationships with major pharmaceutical partners. Financially, the company benefits from a net cash position, meaningful liquidity, and a disclosed runway into late 2027, giving it time to pursue its development agenda. Its emphasis on precision medicine and early intervention further differentiates it within its niche.
The main risks center on persistent operating losses, substantial cash burn, and the absence of commercialized products. Clinical and regulatory uncertainty is significant, particularly in Alzheimer’s and Parkinson’s, where many past programs industry‑wide have failed. Competition from larger companies and other biotechs is intense, and AC Immune remains dependent on external funding, milestone payments, and capital markets to support its pipeline over the long term.
The company’s future is highly event‑driven. Over the next few years, multiple clinical readouts and partnership decisions will likely determine whether its platforms convert into meaningful commercial opportunities. With sufficient cash to reach several major milestones, AC Immune is positioned to potentially unlock substantial value if key programs succeed, but its path remains uncertain and will likely be characterized by significant volatility in both scientific and financial outcomes.
About AC Immune S.A.
https://www.acimmune.comAC Immune SA, a clinical stage biopharmaceutical company, discovers, designs, and develops medicines and diagnostic products for the prevention and treatment of neurodegenerative diseases associated with protein misfolding.
Income Statement
| Period | Revenue | Operating Expense | Net Income | Net Profit Margin | Earnings Per Share | EBITDA |
|---|---|---|---|---|---|---|
| Q4-2025 | $338K ▼ | $14.74M ▼ | $-14.26M ▲ | -4.22K% ▼ | $-0.14 ▲ | $-13.72M ▲ |
| Q3-2025 | $939K ▼ | $17.11M ▼ | $-15.86M ▲ | -1.69K% ▼ | $-0.16 ▲ | $-15.52M ▲ |
| Q2-2025 | $1.31M ▲ | $20.69M ▲ | $-21.19M ▼ | -1.62K% ▲ | $-0.21 ▼ | $-20.52M ▼ |
| Q1-2025 | $990K ▼ | $20.36M ▲ | $-19.03M ▼ | -1.92K% ▼ | $-0.19 ▼ | $-18.36M ▼ |
| Q4-2024 | $1.14M | $19.75M | $-15.8M | -1.39K% | $-0.14 | $-15.23M |
Balance Statement
| Period | Cash & Short-term | Total Assets | Total Liabilities | Total Equity |
|---|---|---|---|---|
| Q4-2025 | $91.52M ▼ | $154.43M ▼ | $109.49M ▲ | $44.93M ▼ |
| Q3-2025 | $108.47M ▼ | $171.61M ▼ | $109.16M ▼ | $62.44M ▼ |
| Q2-2025 | $127.14M ▼ | $190.22M ▼ | $115.48M ▼ | $74.74M ▼ |
| Q1-2025 | $145.61M ▼ | $211.08M ▼ | $116.28M ▼ | $94.8M ▼ |
| Q4-2024 | $165.49M | $230.91M | $118.64M | $112.27M |
Cash Flow Statement
| Period | Net Income | Cash From Operations | Cash From Investing | Cash From Financing | Net Change | Free Cash Flow |
|---|---|---|---|---|---|---|
| Q4-2025 | $-14.26M ▲ | $-16.45M ▲ | $15.94M ▼ | $-259.95K ▼ | $-828.4K ▼ | $-16.55M ▲ |
| Q3-2025 | $-15.86M ▲ | $-18.34M ▼ | $20.63M ▼ | $-254K ▼ | $2.02M ▼ | $-18.4M ▼ |
| Q2-2025 | $-21.19M ▼ | $-15.6M ▲ | $23.88M ▲ | $-247K ▲ | $5.76M ▲ | $-15.97M ▲ |
| Q1-2025 | $-19.03M ▼ | $-18.82M ▼ | $3.03M ▲ | $-258K ▼ | $-16.32M ▼ | $-19.18M ▼ |
| Q4-2024 | $-15.8M | $5.93M | $-3.83M | $-197K | $3.86M | $5.84M |
5-Year Trend Analysis
A comprehensive look at AC Immune S.A.'s financial evolution and strategic trajectory over the past five years.
Key strengths include a focused mission in high‑unmet‑need neurodegenerative diseases, proprietary technology platforms that underpin a diversified pipeline, and strong relationships with major pharmaceutical partners. Financially, the company benefits from a net cash position, meaningful liquidity, and a disclosed runway into late 2027, giving it time to pursue its development agenda. Its emphasis on precision medicine and early intervention further differentiates it within its niche.
The main risks center on persistent operating losses, substantial cash burn, and the absence of commercialized products. Clinical and regulatory uncertainty is significant, particularly in Alzheimer’s and Parkinson’s, where many past programs industry‑wide have failed. Competition from larger companies and other biotechs is intense, and AC Immune remains dependent on external funding, milestone payments, and capital markets to support its pipeline over the long term.
The company’s future is highly event‑driven. Over the next few years, multiple clinical readouts and partnership decisions will likely determine whether its platforms convert into meaningful commercial opportunities. With sufficient cash to reach several major milestones, AC Immune is positioned to potentially unlock substantial value if key programs succeed, but its path remains uncertain and will likely be characterized by significant volatility in both scientific and financial outcomes.

CEO
Andrea Pfeifer
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