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Allogene Therapeutics develops and commercializes genetically engineered allogeneic CAR T cell therapies for cancer, with multiple candidates in clinical trials targeting various hematologic and solid tumors.

Cema-cel is an allogeneic, off-the-shelf CAR T-cell therapy in Phase 2 for large B-cell lymphoma, aiming to provide a rapid, frontline treatment option through its innovative ALPHA3 trial.
In Q2 2025, Allogene Therapeutics presented updated Phase 1b data for its solid tumor candidate, ALLO-316, in renal cell carcinoma at the American Society of Clinical Oncology (ASCO) Annual Meeting. Following the data presentation, the company announced in August that it had aligned with the U.S. Food and Drug Administration (FDA) on a pivotal trial design, signaling a clear path forward for the therapy and sparking discussions around potential partnerships to advance the program.
In a significant strategic move to preserve capital, Allogene Therapeutics announced a 28% workforce reduction and a cost-realignment program. This decision, which follows a 22% layoff in the previous year, is designed to extend the company's financial runway into the second half of 2027, prioritizing key clinical programs amidst a challenging macroeconomic environment.
Overall rating: C
| PEER | PRICE | |
|---|---|---|
ACHV | $7.09 | COMPARE |
AUTL | $1.74 | COMPARE |
EDIT | $2.80 | COMPARE |
AVIR | $5.05 | COMPARE |
KYTX | $6.18 | COMPARE |
CABA | $1.98 | COMPARE |
VNDA | $4.49 | COMPARE |
IPSC | $1.36 | COMPARE |