ANRO
ANRO
Alto Neuroscience, Inc.Income Statement
| Period | Revenue | Operating Expense | Net Income | Net Profit Margin | Earnings Per Share | EBITDA |
|---|---|---|---|---|---|---|
| Q3-2025 | $0 | $14.79M ▼ | $-14.18M ▲ | 0% | $-0.52 ▲ | $-13.37M ▲ |
| Q2-2025 | $0 | $18.58M ▲ | $-17.71M ▼ | 0% | $-0.65 ▼ | $-16.96M ▼ |
| Q1-2025 | $0 | $15.68M ▼ | $-15.17M ▲ | 0% | $-0.56 | $-14.4M ▲ |
| Q4-2024 | $0 | $16.83M ▼ | $-15.2M ▲ | 0% | $-0.56 ▲ | $-14.7M ▲ |
| Q3-2024 | $0 | $18.89M | $-16.78M | 0% | $-0.62 | $-16.31M |
What's going well?
The company is reducing its losses and cutting operating expenses. Earnings per share improved from -$0.65 to -$0.52, and there are no unusual charges distorting results.
What's concerning?
ANRO still has zero revenue and continues to burn cash every quarter. High R&D spending without any sales is risky, and the business remains unprofitable.
Balance Statement
| Period | Cash & Short-term | Total Assets | Total Liabilities | Total Equity |
|---|---|---|---|---|
| Q3-2025 | $137.82M ▼ | $147.01M ▼ | $35.45M ▲ | $111.56M ▼ |
| Q2-2025 | $147.59M ▼ | $157.88M ▼ | $34.47M ▲ | $123.41M ▼ |
| Q1-2025 | $160.75M ▼ | $171.91M ▼ | $32.82M ▲ | $139.1M ▼ |
| Q4-2024 | $168.23M ▼ | $177.54M ▼ | $26.08M ▼ | $151.46M ▼ |
| Q3-2024 | $181.7M | $191.61M | $26.56M | $165.05M |
What's financially strong about this company?
The company sits on a huge cash pile, has almost no short-term debt, and its assets are almost entirely liquid. There is no goodwill or intangible risk, and liabilities are low compared to equity.
What are the financial risks or weaknesses?
Retained earnings are deeply negative, showing the company has lost money over time. Cash and equity both declined this quarter, and there is little sign of growth in productive assets.
Cash Flow Statement
| Period | Net Income | Cash From Operations | Cash From Investing | Cash From Financing | Net Change | Free Cash Flow |
|---|---|---|---|---|---|---|
| Q3-2025 | $-14.18M ▲ | $-9.92M ▲ | $0 | $153K ▼ | $-9.77M ▲ | $-9.92M ▲ |
| Q2-2025 | $-17.71M ▼ | $-13.78M ▲ | $0 ▲ | $613K ▼ | $-13.17M ▼ | $-13.78M ▲ |
| Q1-2025 | $-15.17M ▲ | $-16.56M ▼ | $-24K ▲ | $9.13M ▲ | $-7.47M ▲ | $-16.58M ▼ |
| Q4-2024 | $-15.2M ▲ | $-13.02M ▼ | $-506K ▲ | $49K ▼ | $-13.47M ▼ | $-13.53M ▼ |
| Q3-2024 | $-16.78M | $-11.73M | $-1M | $1.32M | $-11.42M | $-12.73M |
What's strong about this company's cash flow?
Cash burn is shrinking each quarter, and the company still has $137.8 million in cash. No capital spending means cash needs are lower than for most businesses.
What are the cash flow concerns?
The business is still losing real cash every quarter, and is relying on its cash pile and small stock sales to survive. No sign yet of turning cash flow positive, so more funding will be needed if losses continue.
5-Year Trend Analysis
A comprehensive look at Alto Neuroscience, Inc.'s financial evolution and strategic trajectory over the past five years.
Key strengths include a substantially reinforced balance sheet with significant cash and net cash, a focused and differentiated precision‑psychiatry strategy, and a rich pipeline spanning several major neuropsychiatric disorders. The company has built a sizable proprietary dataset and analytics platform, underpinned by growing intellectual property. Its liquidity position provides a meaningful runway to pursue clinical development without immediate financing stress.
Major risks center on clinical, regulatory, and financing uncertainty. The company has no product revenue and rapidly rising operating losses, with deeply negative free cash flow, so it remains dependent on external capital. Clinical trials may fail to show the expected benefit from biomarker‑guided treatment, or regulators may not fully accept the chosen endpoints or patient selection methods. Competition from larger pharmaceutical companies and other innovators in CNS, as well as potential shareholder dilution from future equity raises, are additional concerns.
Looking ahead, Alto’s trajectory will be driven mainly by clinical milestones and its ability to validate the Precision Psychiatry Platform in real‑world trials. The strengthened balance sheet gives it time to execute, but not indefinite flexibility if results disappoint. If upcoming studies show clear efficacy and support the biomarker‑based approach, Alto could move from an interesting concept to a meaningful player in neuropsychiatry. Until then, its financial profile will likely remain that of a high‑burn, pre‑revenue biotech with outcomes highly sensitive to trial data and capital market conditions.
About Alto Neuroscience, Inc.
https://www.altoneuroscience.comAlto Neuroscience, Inc. operates as a clinical-stage biopharmaceutical company that engages in the psychiatry drug development business.
Income Statement
| Period | Revenue | Operating Expense | Net Income | Net Profit Margin | Earnings Per Share | EBITDA |
|---|---|---|---|---|---|---|
| Q3-2025 | $0 | $14.79M ▼ | $-14.18M ▲ | 0% | $-0.52 ▲ | $-13.37M ▲ |
| Q2-2025 | $0 | $18.58M ▲ | $-17.71M ▼ | 0% | $-0.65 ▼ | $-16.96M ▼ |
| Q1-2025 | $0 | $15.68M ▼ | $-15.17M ▲ | 0% | $-0.56 | $-14.4M ▲ |
| Q4-2024 | $0 | $16.83M ▼ | $-15.2M ▲ | 0% | $-0.56 ▲ | $-14.7M ▲ |
| Q3-2024 | $0 | $18.89M | $-16.78M | 0% | $-0.62 | $-16.31M |
What's going well?
The company is reducing its losses and cutting operating expenses. Earnings per share improved from -$0.65 to -$0.52, and there are no unusual charges distorting results.
What's concerning?
ANRO still has zero revenue and continues to burn cash every quarter. High R&D spending without any sales is risky, and the business remains unprofitable.
Balance Statement
| Period | Cash & Short-term | Total Assets | Total Liabilities | Total Equity |
|---|---|---|---|---|
| Q3-2025 | $137.82M ▼ | $147.01M ▼ | $35.45M ▲ | $111.56M ▼ |
| Q2-2025 | $147.59M ▼ | $157.88M ▼ | $34.47M ▲ | $123.41M ▼ |
| Q1-2025 | $160.75M ▼ | $171.91M ▼ | $32.82M ▲ | $139.1M ▼ |
| Q4-2024 | $168.23M ▼ | $177.54M ▼ | $26.08M ▼ | $151.46M ▼ |
| Q3-2024 | $181.7M | $191.61M | $26.56M | $165.05M |
What's financially strong about this company?
The company sits on a huge cash pile, has almost no short-term debt, and its assets are almost entirely liquid. There is no goodwill or intangible risk, and liabilities are low compared to equity.
What are the financial risks or weaknesses?
Retained earnings are deeply negative, showing the company has lost money over time. Cash and equity both declined this quarter, and there is little sign of growth in productive assets.
Cash Flow Statement
| Period | Net Income | Cash From Operations | Cash From Investing | Cash From Financing | Net Change | Free Cash Flow |
|---|---|---|---|---|---|---|
| Q3-2025 | $-14.18M ▲ | $-9.92M ▲ | $0 | $153K ▼ | $-9.77M ▲ | $-9.92M ▲ |
| Q2-2025 | $-17.71M ▼ | $-13.78M ▲ | $0 ▲ | $613K ▼ | $-13.17M ▼ | $-13.78M ▲ |
| Q1-2025 | $-15.17M ▲ | $-16.56M ▼ | $-24K ▲ | $9.13M ▲ | $-7.47M ▲ | $-16.58M ▼ |
| Q4-2024 | $-15.2M ▲ | $-13.02M ▼ | $-506K ▲ | $49K ▼ | $-13.47M ▼ | $-13.53M ▼ |
| Q3-2024 | $-16.78M | $-11.73M | $-1M | $1.32M | $-11.42M | $-12.73M |
What's strong about this company's cash flow?
Cash burn is shrinking each quarter, and the company still has $137.8 million in cash. No capital spending means cash needs are lower than for most businesses.
What are the cash flow concerns?
The business is still losing real cash every quarter, and is relying on its cash pile and small stock sales to survive. No sign yet of turning cash flow positive, so more funding will be needed if losses continue.
5-Year Trend Analysis
A comprehensive look at Alto Neuroscience, Inc.'s financial evolution and strategic trajectory over the past five years.
Key strengths include a substantially reinforced balance sheet with significant cash and net cash, a focused and differentiated precision‑psychiatry strategy, and a rich pipeline spanning several major neuropsychiatric disorders. The company has built a sizable proprietary dataset and analytics platform, underpinned by growing intellectual property. Its liquidity position provides a meaningful runway to pursue clinical development without immediate financing stress.
Major risks center on clinical, regulatory, and financing uncertainty. The company has no product revenue and rapidly rising operating losses, with deeply negative free cash flow, so it remains dependent on external capital. Clinical trials may fail to show the expected benefit from biomarker‑guided treatment, or regulators may not fully accept the chosen endpoints or patient selection methods. Competition from larger pharmaceutical companies and other innovators in CNS, as well as potential shareholder dilution from future equity raises, are additional concerns.
Looking ahead, Alto’s trajectory will be driven mainly by clinical milestones and its ability to validate the Precision Psychiatry Platform in real‑world trials. The strengthened balance sheet gives it time to execute, but not indefinite flexibility if results disappoint. If upcoming studies show clear efficacy and support the biomarker‑based approach, Alto could move from an interesting concept to a meaningful player in neuropsychiatry. Until then, its financial profile will likely remain that of a high‑burn, pre‑revenue biotech with outcomes highly sensitive to trial data and capital market conditions.

CEO
Amit Etkin
Compensation Summary
(Year )
Upcoming Earnings
ETFs Holding This Stock
Summary
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Ratings Snapshot
Rating : C+
Most Recent Analyst Grades
Price Target
Institutional Ownership
ALPHA WAVE GLOBAL, LP
Shares:3.71M
Value:$71.78M
VESTAL POINT CAPITAL, LP
Shares:2.48M
Value:$48.11M
COMMODORE CAPITAL LP
Shares:1.82M
Value:$35.3M
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