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Alto Neuroscience, Inc.

ANRO

Alto Neuroscience, Inc. NYSE
$27.72 6.37% (+1.66)

Market Cap $885.53 M
52w High $28.11
52w Low $2.12
P/E -12.66
Volume 331.19K
Outstanding Shares 31.95M

Income Statement

Period Revenue Operating Expense Net Income Net Profit Margin Earnings Per Share EBITDA
Q4-2025 $0 $16.9M $-16.18M 0% $-0.51 $-16.9M
Q3-2025 $0 $14.79M $-14.18M 0% $-0.52 $-13.37M
Q2-2025 $0 $18.58M $-17.71M 0% $-0.65 $-16.96M
Q1-2025 $0 $15.68M $-15.17M 0% $-0.56 $-14.4M
Q4-2024 $0 $16.83M $-15.2M 0% $-0.56 $-14.7M

Balance Statement

Period Cash & Short-term Total Assets Total Liabilities Total Equity
Q4-2025 $176.48M $184.69M $33.55M $151.14M
Q3-2025 $137.82M $147.01M $35.45M $111.56M
Q2-2025 $147.59M $157.88M $34.47M $123.41M
Q1-2025 $160.75M $171.91M $32.82M $139.1M
Q4-2024 $168.23M $177.54M $26.08M $151.46M

Cash Flow Statement

Period Net Income Cash From Operations Cash From Investing Cash From Financing Net Change Free Cash Flow
Q4-2025 $-16.18M $-11.52M $0 $50.19M $38.67M $-11.52M
Q3-2025 $-14.18M $-9.92M $0 $153K $-9.77M $-9.92M
Q2-2025 $-17.71M $-13.78M $0 $613K $-13.17M $-13.78M
Q1-2025 $-15.17M $-16.56M $-24K $9.13M $-7.47M $-16.58M
Q4-2024 $-15.2M $-13.02M $-506K $49K $-13.47M $-13.53M

5-Year Trend Analysis

A comprehensive look at Alto Neuroscience, Inc.'s financial evolution and strategic trajectory over the past five years.

+ Strengths

Alto combines a strong cash position and low debt with an ambitious, clearly differentiated scientific strategy centered on precision psychiatry. Its balance sheet offers near-term financial flexibility, while its integrated data platform, biomarker expertise, and focused pipeline create a potentially powerful innovation engine. The company is targeting large, highly underserved mental health markets where better treatments and more personalized approaches are badly needed.

! Risks

Key risks include sustained operating losses, heavy cash burn, and dependence on new financing or partnership capital, all in the absence of current revenue. Scientifically, the approach is complex and may face clinical, regulatory, and adoption challenges, especially around the acceptance of biomarker-based patient selection. Competitive pressure from other innovators and large pharma, along with the inherent uncertainty of psychiatric drug development, adds further execution risk.

Outlook

The forward picture is that of a high-risk, high-uncertainty clinical-stage biotech with meaningful scientific potential. In the near to medium term, progress will be judged mainly by clinical trial readouts, validation of the Precision Psychiatry Platform, and the company’s ability to manage its cash runway. Long-term outcomes will depend on whether Alto can convert its technological and data advantages into approved therapies and, eventually, a durable and scalable commercial business.