ANTX
ANTX
AN2 Therapeutics, Inc.Income Statement
| Period | Revenue | Operating Expense | Net Income | Net Profit Margin | Earnings Per Share | EBITDA |
|---|---|---|---|---|---|---|
| Q4-2025 | $0 | $9.32M ▼ | $-8.71M ▲ | 0% | $-0.29 ▲ | $-10M ▼ |
| Q3-2025 | $0 | $10.04M ▲ | $-9.35M ▼ | 0% | $-0.31 ▼ | $-9.35M ▼ |
| Q2-2025 | $0 | $7.22M ▼ | $-6.46M ▲ | 0% | $-0.21 ▲ | $-7.22M ▲ |
| Q1-2025 | $0 | $11.54M ▲ | $-10.65M ▼ | 0% | $-0.35 ▼ | $-11.54M ▼ |
| Q4-2024 | $0 | $8.6M | $-7.52M | 0% | $-0.25 | $0 |
Balance Statement
| Period | Cash & Short-term | Total Assets | Total Liabilities | Total Equity |
|---|---|---|---|---|
| Q4-2025 | $58M ▼ | $61.95M ▼ | $8.89M ▲ | $53.06M ▼ |
| Q3-2025 | $61.92M ▼ | $67.23M ▼ | $6.86M ▼ | $60.38M ▼ |
| Q2-2025 | $62.92M ▼ | $75.83M ▼ | $6.98M ▼ | $68.84M ▼ |
| Q1-2025 | $67.06M ▼ | $81.34M ▼ | $8.01M ▼ | $73.33M ▼ |
| Q4-2024 | $83.62M | $92.09M | $10.24M | $81.85M |
Cash Flow Statement
| Period | Net Income | Cash From Operations | Cash From Investing | Cash From Financing | Net Change | Free Cash Flow |
|---|---|---|---|---|---|---|
| Q4-2025 | $-8.71M ▲ | $-5.24M ▲ | $7.17M ▲ | $0 ▼ | $1.94M ▲ | $-5.24M ▲ |
| Q3-2025 | $-9.35M ▼ | $-6.38M ▲ | $6.11M ▲ | $48K ▲ | $-217K ▲ | $-6.38M ▲ |
| Q2-2025 | $-6.46M ▲ | $-7.6M ▲ | $5.83M ▼ | $0 ▼ | $-1.76M ▼ | $-7.6M ▲ |
| Q1-2025 | $-10.65M ▼ | $-10.62M ▼ | $9.19M ▲ | $65K ▲ | $-1.37M ▲ | $-10.62M ▼ |
| Q4-2024 | $-7.52M | $-5.27M | $-6.88M | $0 | $-12.15M | $-5.27M |
5-Year Trend Analysis
A comprehensive look at AN2 Therapeutics, Inc.'s financial evolution and strategic trajectory over the past five years.
Key strengths include a strong cash and liquidity position with no financial debt, a focused and innovation‑driven R&D strategy, and a differentiated boron chemistry platform that could unlock novel treatments in infectious disease and oncology. Regulatory designations and targeting of diseases with high unmet need strengthen the potential value of successful programs. The balance sheet provides some runway to pursue these opportunities without immediate pressure from lenders.
Major risks center on sustained losses, significant negative cash flow from operations, and complete dependence on unproven drug candidates for future revenue. Clinical, regulatory, and competitive uncertainties are high, particularly given the crowded nature of oncology and the economic challenges in antibiotic markets. Large accumulated losses and the absence of current revenue mean that additional capital will likely be required over time if commercialization is delayed or programs underperform.
The outlook for ANTX is highly binary and tightly linked to clinical milestones. In the near and medium term, investors and stakeholders will focus on readouts from trials of epetraborole in serious infections and polycythemia vera, as well as on signs that earlier‑stage programs can advance. Financially, the company appears reasonably well positioned for now due to strong liquidity and lack of debt, but the business remains in a development‑only phase. Long‑term prospects will depend on whether the boron chemistry platform can translate into approved, commercially viable medicines before the cash runway and market patience are exhausted.
About AN2 Therapeutics, Inc.
https://www.an2therapeutics.comAN2 Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on developing treatments for rare, chronic, and serious infectious diseases. It is developing epetraborole, a once-daily oral treatment for patients with chronic non-tuberculous mycobacterial lung disease. The company was incorporated in 2017 and is headquartered in Menlo Park, California.
Income Statement
| Period | Revenue | Operating Expense | Net Income | Net Profit Margin | Earnings Per Share | EBITDA |
|---|---|---|---|---|---|---|
| Q4-2025 | $0 | $9.32M ▼ | $-8.71M ▲ | 0% | $-0.29 ▲ | $-10M ▼ |
| Q3-2025 | $0 | $10.04M ▲ | $-9.35M ▼ | 0% | $-0.31 ▼ | $-9.35M ▼ |
| Q2-2025 | $0 | $7.22M ▼ | $-6.46M ▲ | 0% | $-0.21 ▲ | $-7.22M ▲ |
| Q1-2025 | $0 | $11.54M ▲ | $-10.65M ▼ | 0% | $-0.35 ▼ | $-11.54M ▼ |
| Q4-2024 | $0 | $8.6M | $-7.52M | 0% | $-0.25 | $0 |
Balance Statement
| Period | Cash & Short-term | Total Assets | Total Liabilities | Total Equity |
|---|---|---|---|---|
| Q4-2025 | $58M ▼ | $61.95M ▼ | $8.89M ▲ | $53.06M ▼ |
| Q3-2025 | $61.92M ▼ | $67.23M ▼ | $6.86M ▼ | $60.38M ▼ |
| Q2-2025 | $62.92M ▼ | $75.83M ▼ | $6.98M ▼ | $68.84M ▼ |
| Q1-2025 | $67.06M ▼ | $81.34M ▼ | $8.01M ▼ | $73.33M ▼ |
| Q4-2024 | $83.62M | $92.09M | $10.24M | $81.85M |
Cash Flow Statement
| Period | Net Income | Cash From Operations | Cash From Investing | Cash From Financing | Net Change | Free Cash Flow |
|---|---|---|---|---|---|---|
| Q4-2025 | $-8.71M ▲ | $-5.24M ▲ | $7.17M ▲ | $0 ▼ | $1.94M ▲ | $-5.24M ▲ |
| Q3-2025 | $-9.35M ▼ | $-6.38M ▲ | $6.11M ▲ | $48K ▲ | $-217K ▲ | $-6.38M ▲ |
| Q2-2025 | $-6.46M ▲ | $-7.6M ▲ | $5.83M ▼ | $0 ▼ | $-1.76M ▼ | $-7.6M ▲ |
| Q1-2025 | $-10.65M ▼ | $-10.62M ▼ | $9.19M ▲ | $65K ▲ | $-1.37M ▲ | $-10.62M ▼ |
| Q4-2024 | $-7.52M | $-5.27M | $-6.88M | $0 | $-12.15M | $-5.27M |
5-Year Trend Analysis
A comprehensive look at AN2 Therapeutics, Inc.'s financial evolution and strategic trajectory over the past five years.
Key strengths include a strong cash and liquidity position with no financial debt, a focused and innovation‑driven R&D strategy, and a differentiated boron chemistry platform that could unlock novel treatments in infectious disease and oncology. Regulatory designations and targeting of diseases with high unmet need strengthen the potential value of successful programs. The balance sheet provides some runway to pursue these opportunities without immediate pressure from lenders.
Major risks center on sustained losses, significant negative cash flow from operations, and complete dependence on unproven drug candidates for future revenue. Clinical, regulatory, and competitive uncertainties are high, particularly given the crowded nature of oncology and the economic challenges in antibiotic markets. Large accumulated losses and the absence of current revenue mean that additional capital will likely be required over time if commercialization is delayed or programs underperform.
The outlook for ANTX is highly binary and tightly linked to clinical milestones. In the near and medium term, investors and stakeholders will focus on readouts from trials of epetraborole in serious infections and polycythemia vera, as well as on signs that earlier‑stage programs can advance. Financially, the company appears reasonably well positioned for now due to strong liquidity and lack of debt, but the business remains in a development‑only phase. Long‑term prospects will depend on whether the boron chemistry platform can translate into approved, commercially viable medicines before the cash runway and market patience are exhausted.

CEO
Eric E. Easom
Compensation Summary
(Year 2024)
Upcoming Earnings
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Rating : C+
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