ANTX
ANTX
AN2 Therapeutics, Inc.Income Statement
| Period | Revenue | Operating Expense | Net Income | Net Profit Margin | Earnings Per Share | EBITDA |
|---|---|---|---|---|---|---|
| Q3-2025 | $0 | $10.04M ▲ | $-9.35M ▼ | 0% | $-0.31 ▼ | $-9.35M ▼ |
| Q2-2025 | $0 | $7.22M ▼ | $-6.46M ▲ | 0% | $-0.21 ▲ | $-7.22M ▲ |
| Q1-2025 | $0 | $11.54M ▲ | $-10.65M ▼ | 0% | $-0.35 ▼ | $-11.54M ▼ |
| Q4-2024 | $0 | $8.6M ▼ | $-7.52M ▲ | 0% | $-0.25 ▲ | $0 ▲ |
| Q3-2024 | $0 | $14.01M | $-12.75M | 0% | $-0.43 | $-11.77M |
What's going well?
The company is investing heavily in research and development, which could lead to future products or breakthroughs. Administrative costs were trimmed this quarter.
What's concerning?
There is still no revenue, and losses are getting much bigger as spending rises. Without sales, the company will need to keep raising money just to stay afloat.
Balance Statement
| Period | Cash & Short-term | Total Assets | Total Liabilities | Total Equity |
|---|---|---|---|---|
| Q3-2025 | $61.92M ▼ | $67.23M ▼ | $6.86M ▼ | $60.38M ▼ |
| Q2-2025 | $62.92M ▼ | $75.83M ▼ | $6.98M ▼ | $68.84M ▼ |
| Q1-2025 | $67.06M ▼ | $81.34M ▼ | $8.01M ▼ | $73.33M ▼ |
| Q4-2024 | $83.62M ▼ | $92.09M ▼ | $10.24M ▲ | $81.85M ▼ |
| Q3-2024 | $93.43M | $97.69M | $10.02M | $87.67M |
What's financially strong about this company?
ANTX has no debt and a huge cash cushion compared to its tiny liabilities. Its assets are almost all in cash and short-term investments, making it very safe from a liquidity standpoint.
What are the financial risks or weaknesses?
Book value and total assets are declining, and the company has a long history of losses (negative retained earnings). No sign of profitable operations yet.
Cash Flow Statement
| Period | Net Income | Cash From Operations | Cash From Investing | Cash From Financing | Net Change | Free Cash Flow |
|---|---|---|---|---|---|---|
| Q3-2025 | $-9.35M ▼ | $-6.38M ▲ | $6.11M ▲ | $48K ▲ | $-217K ▲ | $-6.38M ▲ |
| Q2-2025 | $-6.46M ▲ | $-7.6M ▲ | $5.83M ▼ | $0 ▼ | $-1.76M ▼ | $-7.6M ▲ |
| Q1-2025 | $-10.65M ▼ | $-10.62M ▼ | $9.19M ▲ | $65K ▲ | $-1.37M ▲ | $-10.62M ▼ |
| Q4-2024 | $-7.52M ▲ | $-5.27M ▲ | $-6.88M ▼ | $0 ▼ | $-12.15M ▼ | $-5.27M ▲ |
| Q3-2024 | $-12.75M | $-12.01M | $18.72M | $23K | $6.74M | $-12.01M |
What's strong about this company's cash flow?
Cash burn is getting smaller each quarter, and the company still has $18 million in cash. Working capital changes helped slow the cash drain this time.
What are the cash flow concerns?
The company is still losing real cash every quarter, and the improvement is mostly from timing tricks like stretching payables. Without real profits, more funding will be needed soon.
5-Year Trend Analysis
A comprehensive look at AN2 Therapeutics, Inc.'s financial evolution and strategic trajectory over the past five years.
Key positives include a strong liquidity position with substantial cash and no meaningful debt, a differentiated boron chemistry platform, and a pipeline aimed at serious, underserved diseases where even modest success could be impactful. The company has shown an ability to raise capital and secure non‑dilutive funding and partnerships, and has begun to adjust spending after its major setback, indicating a willingness to adapt strategy and control costs.
Major risks center on sustained losses, ongoing cash burn, and complete dependence on future clinical and regulatory success. The high‑profile Phase 3 failure highlights the scientific and execution risk inherent in the model. If upcoming trials in new indications or oncology do not deliver convincing results, ANTX could face pressure on both financing options and strategic direction. Dilution risk remains structurally high, and pricing, reimbursement, and adoption challenges are common in anti‑infective and rare‑disease markets.
The outlook for ANTX is highly uncertain and strongly binary in nature. On one hand, the company has enough cash to pursue its pivot strategy over the next several years and a platform that could, in principle, generate multiple valuable drugs across infectious disease and oncology. On the other hand, the business remains pre‑revenue, unprofitable, and heavily reliant on unproven assets. Future developments—especially clinical readouts in Chagas disease, new NTM and melioidosis indications, and the first oncology candidate—will be critical in determining whether ANTX can transition from a cash‑burning R&D platform to a more sustainable biopharmaceutical enterprise.
About AN2 Therapeutics, Inc.
https://www.an2therapeutics.comAN2 Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on developing treatments for rare, chronic, and serious infectious diseases. It is developing epetraborole, a once-daily oral treatment for patients with chronic non-tuberculous mycobacterial lung disease. The company was incorporated in 2017 and is headquartered in Menlo Park, California.
Income Statement
| Period | Revenue | Operating Expense | Net Income | Net Profit Margin | Earnings Per Share | EBITDA |
|---|---|---|---|---|---|---|
| Q3-2025 | $0 | $10.04M ▲ | $-9.35M ▼ | 0% | $-0.31 ▼ | $-9.35M ▼ |
| Q2-2025 | $0 | $7.22M ▼ | $-6.46M ▲ | 0% | $-0.21 ▲ | $-7.22M ▲ |
| Q1-2025 | $0 | $11.54M ▲ | $-10.65M ▼ | 0% | $-0.35 ▼ | $-11.54M ▼ |
| Q4-2024 | $0 | $8.6M ▼ | $-7.52M ▲ | 0% | $-0.25 ▲ | $0 ▲ |
| Q3-2024 | $0 | $14.01M | $-12.75M | 0% | $-0.43 | $-11.77M |
What's going well?
The company is investing heavily in research and development, which could lead to future products or breakthroughs. Administrative costs were trimmed this quarter.
What's concerning?
There is still no revenue, and losses are getting much bigger as spending rises. Without sales, the company will need to keep raising money just to stay afloat.
Balance Statement
| Period | Cash & Short-term | Total Assets | Total Liabilities | Total Equity |
|---|---|---|---|---|
| Q3-2025 | $61.92M ▼ | $67.23M ▼ | $6.86M ▼ | $60.38M ▼ |
| Q2-2025 | $62.92M ▼ | $75.83M ▼ | $6.98M ▼ | $68.84M ▼ |
| Q1-2025 | $67.06M ▼ | $81.34M ▼ | $8.01M ▼ | $73.33M ▼ |
| Q4-2024 | $83.62M ▼ | $92.09M ▼ | $10.24M ▲ | $81.85M ▼ |
| Q3-2024 | $93.43M | $97.69M | $10.02M | $87.67M |
What's financially strong about this company?
ANTX has no debt and a huge cash cushion compared to its tiny liabilities. Its assets are almost all in cash and short-term investments, making it very safe from a liquidity standpoint.
What are the financial risks or weaknesses?
Book value and total assets are declining, and the company has a long history of losses (negative retained earnings). No sign of profitable operations yet.
Cash Flow Statement
| Period | Net Income | Cash From Operations | Cash From Investing | Cash From Financing | Net Change | Free Cash Flow |
|---|---|---|---|---|---|---|
| Q3-2025 | $-9.35M ▼ | $-6.38M ▲ | $6.11M ▲ | $48K ▲ | $-217K ▲ | $-6.38M ▲ |
| Q2-2025 | $-6.46M ▲ | $-7.6M ▲ | $5.83M ▼ | $0 ▼ | $-1.76M ▼ | $-7.6M ▲ |
| Q1-2025 | $-10.65M ▼ | $-10.62M ▼ | $9.19M ▲ | $65K ▲ | $-1.37M ▲ | $-10.62M ▼ |
| Q4-2024 | $-7.52M ▲ | $-5.27M ▲ | $-6.88M ▼ | $0 ▼ | $-12.15M ▼ | $-5.27M ▲ |
| Q3-2024 | $-12.75M | $-12.01M | $18.72M | $23K | $6.74M | $-12.01M |
What's strong about this company's cash flow?
Cash burn is getting smaller each quarter, and the company still has $18 million in cash. Working capital changes helped slow the cash drain this time.
What are the cash flow concerns?
The company is still losing real cash every quarter, and the improvement is mostly from timing tricks like stretching payables. Without real profits, more funding will be needed soon.
5-Year Trend Analysis
A comprehensive look at AN2 Therapeutics, Inc.'s financial evolution and strategic trajectory over the past five years.
Key positives include a strong liquidity position with substantial cash and no meaningful debt, a differentiated boron chemistry platform, and a pipeline aimed at serious, underserved diseases where even modest success could be impactful. The company has shown an ability to raise capital and secure non‑dilutive funding and partnerships, and has begun to adjust spending after its major setback, indicating a willingness to adapt strategy and control costs.
Major risks center on sustained losses, ongoing cash burn, and complete dependence on future clinical and regulatory success. The high‑profile Phase 3 failure highlights the scientific and execution risk inherent in the model. If upcoming trials in new indications or oncology do not deliver convincing results, ANTX could face pressure on both financing options and strategic direction. Dilution risk remains structurally high, and pricing, reimbursement, and adoption challenges are common in anti‑infective and rare‑disease markets.
The outlook for ANTX is highly uncertain and strongly binary in nature. On one hand, the company has enough cash to pursue its pivot strategy over the next several years and a platform that could, in principle, generate multiple valuable drugs across infectious disease and oncology. On the other hand, the business remains pre‑revenue, unprofitable, and heavily reliant on unproven assets. Future developments—especially clinical readouts in Chagas disease, new NTM and melioidosis indications, and the first oncology candidate—will be critical in determining whether ANTX can transition from a cash‑burning R&D platform to a more sustainable biopharmaceutical enterprise.

CEO
Eric E. Easom
Compensation Summary
(Year 2024)
Upcoming Earnings
ETFs Holding This Stock
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Ratings Snapshot
Rating : C
Most Recent Analyst Grades
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Price Target
Institutional Ownership
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Value:$1.63M
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