CBIO
CBIO
Crescent Biopharma, Inc.Income Statement
| Period | Revenue | Operating Expense | Net Income | Net Profit Margin | Earnings Per Share | EBITDA |
|---|---|---|---|---|---|---|
| Q4-2025 | $-30.56M ▼ | $74.38M ▲ | $-101.2M ▼ | 331.11% ▲ | $-12.82K ▼ | $-99.29M ▼ |
| Q3-2025 | $30.56M ▲ | $25.89M ▲ | $-24.61M ▼ | -80.51% ▼ | $0.04 ▲ | $-24.58M ▼ |
| Q2-2025 | $0 | $21.03M ▲ | $-21.79M ▼ | 0% | $-0.28 ▼ | $-20.72M ▼ |
| Q1-2025 | $0 | $2.4M ▼ | $-2.34M ▲ | 0% | $-0.04 ▲ | $-2.4M ▲ |
| Q4-2024 | $0 | $40.01B | $-7.22M | 0% | $-0.11 | $-17.02M |
Balance Statement
| Period | Cash & Short-term | Total Assets | Total Liabilities | Total Equity |
|---|---|---|---|---|
| Q4-2025 | $213.19M ▲ | $240.29M ▲ | $37.28M ▲ | $203.01M ▲ |
| Q3-2025 | $133.26M ▼ | $138.27M ▼ | $21.63M ▲ | $116.64M ▼ |
| Q2-2025 | $152.65M ▲ | $157.43M ▲ | $18.18M ▲ | $139.25M ▲ |
| Q1-2025 | $5.61M ▼ | $5.99M ▼ | $2.62M ▼ | $3.38M ▼ |
| Q4-2024 | $10.72M | $11.09M | $5.78M | $5.31M |
Cash Flow Statement
| Period | Net Income | Cash From Operations | Cash From Investing | Cash From Financing | Net Change | Free Cash Flow |
|---|---|---|---|---|---|---|
| Q4-2025 | $22.77M ▲ | $22.21M ▲ | $-661K ▼ | $177.24M ▲ | $172.9M ▲ | $22.13M ▲ |
| Q3-2025 | $-24.61M ▼ | $-17.52M ▲ | $-586K ▼ | $-1.27M ▼ | $-19.38M ▼ | $-18.11M ▲ |
| Q2-2025 | $-21.79M ▼ | $-22.16M ▼ | $-140K ▼ | $145.39M ▲ | $147.03M ▲ | $-22.3M ▼ |
| Q1-2025 | $-2.34M ▲ | $-5.11M ▲ | $0 ▼ | $0 ▼ | $-5.11M ▼ | $-5.11M ▼ |
| Q4-2024 | $-37.88M | $-6.27M | $30K | $41.03M | $34.77M | $-3.7M |
Revenue by Products
| Product | Q2-2025 | Q3-2025 | Q4-2025 |
|---|---|---|---|
Product | $0 ▲ | $30.00M ▲ | $0 ▼ |
Reportable Segment | $0 ▲ | $0 ▲ | $10.00M ▲ |
Q1 2024 Earnings Call Summary
Read Call Summary5-Year Trend Analysis
A comprehensive look at Crescent Biopharma, Inc.'s financial evolution and strategic trajectory over the past five years.
Crescent combines a clean, cash-rich, low-debt balance sheet with a focused, innovation-heavy oncology pipeline and a meaningful strategic partnership. Its cost structure emphasizes R&D over overhead, signaling that capital is being directed toward scientific value creation. The leadership team and partner network provide industry expertise and access to technologies that a small company might otherwise struggle to build on its own.
The main risks are fundamental: no revenue, large and ongoing losses, negative free cash flow, and heavy dependence on external financing. Scientifically, the pipeline is still in early clinical stages, where failure rates are high. Competitive pressure in immuno-oncology and ADCs is intense, and even positive data may not guarantee a strong commercial foothold if rival products perform better or reach the market earlier. Dilution risk for existing shareholders is also structurally present as long as the company must raise new equity capital.
Looking ahead, Crescent’s trajectory will be determined largely by clinical data and continued access to capital. In the near to medium term, investors and stakeholders are likely to focus on safety and early efficacy readouts from the lead programs, as these will shape perceptions of the company’s scientific merit and partnering potential. If results are encouraging and financing remains available, the company could transition over time from a pure R&D story to a late-stage development or partnership-driven model. Conversely, setbacks in the clinic or a less supportive funding environment would materially weaken the outlook. Overall, the story is high-risk and highly dependent on future scientific proof points.
About Crescent Biopharma, Inc.
https://crescentbiopharma.comCrescent Biopharma, Inc., a biotechnology company, researches and develops cancer therapy candidates. Its pipeline includes CR-001, a proprietary anti-PD-1/anti-VEGF bispecific antibody to treat solid tumors; and CR-002, and CR-003.
Income Statement
| Period | Revenue | Operating Expense | Net Income | Net Profit Margin | Earnings Per Share | EBITDA |
|---|---|---|---|---|---|---|
| Q4-2025 | $-30.56M ▼ | $74.38M ▲ | $-101.2M ▼ | 331.11% ▲ | $-12.82K ▼ | $-99.29M ▼ |
| Q3-2025 | $30.56M ▲ | $25.89M ▲ | $-24.61M ▼ | -80.51% ▼ | $0.04 ▲ | $-24.58M ▼ |
| Q2-2025 | $0 | $21.03M ▲ | $-21.79M ▼ | 0% | $-0.28 ▼ | $-20.72M ▼ |
| Q1-2025 | $0 | $2.4M ▼ | $-2.34M ▲ | 0% | $-0.04 ▲ | $-2.4M ▲ |
| Q4-2024 | $0 | $40.01B | $-7.22M | 0% | $-0.11 | $-17.02M |
Balance Statement
| Period | Cash & Short-term | Total Assets | Total Liabilities | Total Equity |
|---|---|---|---|---|
| Q4-2025 | $213.19M ▲ | $240.29M ▲ | $37.28M ▲ | $203.01M ▲ |
| Q3-2025 | $133.26M ▼ | $138.27M ▼ | $21.63M ▲ | $116.64M ▼ |
| Q2-2025 | $152.65M ▲ | $157.43M ▲ | $18.18M ▲ | $139.25M ▲ |
| Q1-2025 | $5.61M ▼ | $5.99M ▼ | $2.62M ▼ | $3.38M ▼ |
| Q4-2024 | $10.72M | $11.09M | $5.78M | $5.31M |
Cash Flow Statement
| Period | Net Income | Cash From Operations | Cash From Investing | Cash From Financing | Net Change | Free Cash Flow |
|---|---|---|---|---|---|---|
| Q4-2025 | $22.77M ▲ | $22.21M ▲ | $-661K ▼ | $177.24M ▲ | $172.9M ▲ | $22.13M ▲ |
| Q3-2025 | $-24.61M ▼ | $-17.52M ▲ | $-586K ▼ | $-1.27M ▼ | $-19.38M ▼ | $-18.11M ▲ |
| Q2-2025 | $-21.79M ▼ | $-22.16M ▼ | $-140K ▼ | $145.39M ▲ | $147.03M ▲ | $-22.3M ▼ |
| Q1-2025 | $-2.34M ▲ | $-5.11M ▲ | $0 ▼ | $0 ▼ | $-5.11M ▼ | $-5.11M ▼ |
| Q4-2024 | $-37.88M | $-6.27M | $30K | $41.03M | $34.77M | $-3.7M |
Revenue by Products
| Product | Q2-2025 | Q3-2025 | Q4-2025 |
|---|---|---|---|
Product | $0 ▲ | $30.00M ▲ | $0 ▼ |
Reportable Segment | $0 ▲ | $0 ▲ | $10.00M ▲ |
Q1 2024 Earnings Call Summary
Read Call Summary5-Year Trend Analysis
A comprehensive look at Crescent Biopharma, Inc.'s financial evolution and strategic trajectory over the past five years.
Crescent combines a clean, cash-rich, low-debt balance sheet with a focused, innovation-heavy oncology pipeline and a meaningful strategic partnership. Its cost structure emphasizes R&D over overhead, signaling that capital is being directed toward scientific value creation. The leadership team and partner network provide industry expertise and access to technologies that a small company might otherwise struggle to build on its own.
The main risks are fundamental: no revenue, large and ongoing losses, negative free cash flow, and heavy dependence on external financing. Scientifically, the pipeline is still in early clinical stages, where failure rates are high. Competitive pressure in immuno-oncology and ADCs is intense, and even positive data may not guarantee a strong commercial foothold if rival products perform better or reach the market earlier. Dilution risk for existing shareholders is also structurally present as long as the company must raise new equity capital.
Looking ahead, Crescent’s trajectory will be determined largely by clinical data and continued access to capital. In the near to medium term, investors and stakeholders are likely to focus on safety and early efficacy readouts from the lead programs, as these will shape perceptions of the company’s scientific merit and partnering potential. If results are encouraging and financing remains available, the company could transition over time from a pure R&D story to a late-stage development or partnership-driven model. Conversely, setbacks in the clinic or a less supportive funding environment would materially weaken the outlook. Overall, the story is high-risk and highly dependent on future scientific proof points.

CEO
Joshua T. Brumm
Compensation Summary
(Year 2023)
Split Record
| Date | Type | Ratio |
|---|---|---|
| 2025-06-16 | Reverse | 1:100 |
ETFs Holding This Stock
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Ratings Snapshot
Rating : C
Most Recent Analyst Grades
Grade Summary
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Price Target
Institutional Ownership
FMR LLC
Shares:4.13M
Value:$49.97M
BVF INC/IL
Shares:2.75M
Value:$33.23M
FAIRMOUNT FUNDS MANAGEMENT LLC
Shares:2.75M
Value:$33.22M
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