CRBU
CRBU
Caribou Biosciences, Inc.Income Statement
| Period | Revenue | Operating Expense | Net Income | Net Profit Margin | Earnings Per Share | EBITDA |
|---|---|---|---|---|---|---|
| Q3-2025 | $2.2M ▼ | $30.97M ▼ | $-27.55M ▲ | -1.25K% ▲ | $-0.3 ▲ | $-26.92M ▲ |
| Q2-2025 | $2.67M ▲ | $50.24M ▲ | $-54.1M ▼ | -2.03K% ▼ | $-0.58 ▼ | $-34.26M ▲ |
| Q1-2025 | $2.35M ▲ | $45.27M ▲ | $-39.99M ▼ | -1.7K% ▲ | $-0.43 ▼ | $-41.75M ▼ |
| Q4-2024 | $2.08M ▲ | $11.09M ▼ | $-35.49M ▼ | -1.71K% ▲ | $-0.39 ▼ | $-37.09M ▼ |
| Q3-2024 | $2.02M | $40.26M | $-34.68M | -1.71K% | $-0.38 | $-37.06M |
What's going well?
The company managed to cut its net loss by half this quarter by slashing expenses, especially in R&D and admin. Operating losses are shrinking, and there was a small boost from other income.
What's concerning?
Revenue is tiny and dropped 18% this quarter, with gross profit falling even faster. The business still loses far more than it brings in, and margins are very weak.
Balance Statement
| Period | Cash & Short-term | Total Assets | Total Liabilities | Total Equity |
|---|---|---|---|---|
| Q3-2025 | $147.26M ▼ | $194.98M ▼ | $53.14M ▼ | $141.84M ▼ |
| Q2-2025 | $183.95M ▼ | $220.9M ▼ | $54.77M ▼ | $166.13M ▼ |
| Q1-2025 | $208.47M ▼ | $273.66M ▼ | $56.43M ▼ | $217.22M ▼ |
| Q4-2024 | $209.54M ▼ | $313.31M ▼ | $60.36M ▼ | $252.95M ▼ |
| Q3-2024 | $228.18M | $344.33M | $63.13M | $281.2M |
What's financially strong about this company?
Most assets are in cash and investments, with no risky goodwill or intangibles. Debt is low and mostly long-term, and the company can easily cover its bills in the near term.
What are the financial risks or weaknesses?
Cash and investments are dropping quickly, and the company has a long history of losses. If this trend continues, they may need to raise more money, which could dilute shareholders.
Cash Flow Statement
| Period | Net Income | Cash From Operations | Cash From Investing | Cash From Financing | Net Change | Free Cash Flow |
|---|---|---|---|---|---|---|
| Q3-2025 | $-27.55M ▲ | $-25.18M ▲ | $10.85M ▼ | $277K ▲ | $-14.06M ▼ | $-25.3M ▲ |
| Q2-2025 | $-54.1M ▼ | $-28.26M ▲ | $24.04M ▼ | $6K ▼ | $-4.22M ▼ | $-28.68M ▲ |
| Q1-2025 | $-39.99M ▼ | $-36.73M ▼ | $49.38M ▲ | $468K ▼ | $13.12M ▲ | $-37.77M ▼ |
| Q4-2024 | $-35.49M ▼ | $-35.47M ▼ | $15.93M ▼ | $3.86M ▲ | $-15.68M ▼ | $-35.99M ▼ |
| Q3-2024 | $-34.68M | $-32.66M | $26.52M | $244K | $-5.9M | $-33.33M |
What's strong about this company's cash flow?
Losses and cash burn are shrinking compared to last quarter, showing some improvement. Capital spending is very low, so most cash goes to running the business.
What are the cash flow concerns?
The company is burning through cash with no sign of self-sufficiency, and the cash balance is running dangerously low. It will need to raise more money soon to survive.
Revenue by Products
| Product | Q1-2025 | Q2-2025 | Q3-2025 |
|---|---|---|---|
Reportable Segment | $0 ▲ | $0 ▲ | $0 ▲ |
Revenue by Geography
| Region | Q4-2024 | Q1-2025 | Q2-2025 | Q3-2025 |
|---|---|---|---|---|
NonUS | $0 ▲ | $0 ▲ | $0 ▲ | $0 ▲ |
UNITED STATES | $10.00M ▲ | $0 ▼ | $0 ▲ | $0 ▲ |
5-Year Trend Analysis
A comprehensive look at Caribou Biosciences, Inc.'s financial evolution and strategic trajectory over the past five years.
Caribou’s main strengths lie in its cutting-edge gene-editing technology, strong scientific foundation, and focused pipeline of differentiated allogeneic CAR‑T therapies. It has built a meaningful patent estate, attracted high-profile scientific leadership, and secured validation through industry partnerships. Financially, it still maintains a positive equity base and a liquidity position that, while declining, remains stronger than many early-stage peers. These factors support its ability to pursue ambitious innovation in a high-potential field.
The company faces significant risks on multiple fronts. Its income statement shows rapidly expanding losses and no line of sight yet to profitability, while its cash flow profile reflects accelerating burn and growing dependence on external capital. The balance sheet, though currently adequate, is weakening as cash is consumed and net debt emerges. Overlaying this are the usual biotech hazards: clinical failure, regulatory setbacks, intense competition, and the potential difficulty of raising additional funds if market sentiment or trial data turn unfavorable.
The outlook for Caribou is highly dependent on the success of its lead programs and its ability to manage cash prudently. If CB‑010 and CB‑011 deliver strong and durable clinical results, the company could move toward pivotal trials, attract new partnerships, and improve its financing options, potentially transforming its financial profile over time. If results are disappointing or delayed, the combination of rising losses and shrinking liquidity could become more problematic. Overall, the story is one of high scientific promise paired with substantial financial and execution risk, typical of a clinical-stage biotech at a critical inflection point.
About Caribou Biosciences, Inc.
https://cariboubio.comCaribou Biosciences, Inc., a clinical-stage biopharmaceutical company, engages in the development of genome-edited allogeneic cell therapies for the treatment of hematologic malignancies and solid tumors in the United States and internationally.
Income Statement
| Period | Revenue | Operating Expense | Net Income | Net Profit Margin | Earnings Per Share | EBITDA |
|---|---|---|---|---|---|---|
| Q3-2025 | $2.2M ▼ | $30.97M ▼ | $-27.55M ▲ | -1.25K% ▲ | $-0.3 ▲ | $-26.92M ▲ |
| Q2-2025 | $2.67M ▲ | $50.24M ▲ | $-54.1M ▼ | -2.03K% ▼ | $-0.58 ▼ | $-34.26M ▲ |
| Q1-2025 | $2.35M ▲ | $45.27M ▲ | $-39.99M ▼ | -1.7K% ▲ | $-0.43 ▼ | $-41.75M ▼ |
| Q4-2024 | $2.08M ▲ | $11.09M ▼ | $-35.49M ▼ | -1.71K% ▲ | $-0.39 ▼ | $-37.09M ▼ |
| Q3-2024 | $2.02M | $40.26M | $-34.68M | -1.71K% | $-0.38 | $-37.06M |
What's going well?
The company managed to cut its net loss by half this quarter by slashing expenses, especially in R&D and admin. Operating losses are shrinking, and there was a small boost from other income.
What's concerning?
Revenue is tiny and dropped 18% this quarter, with gross profit falling even faster. The business still loses far more than it brings in, and margins are very weak.
Balance Statement
| Period | Cash & Short-term | Total Assets | Total Liabilities | Total Equity |
|---|---|---|---|---|
| Q3-2025 | $147.26M ▼ | $194.98M ▼ | $53.14M ▼ | $141.84M ▼ |
| Q2-2025 | $183.95M ▼ | $220.9M ▼ | $54.77M ▼ | $166.13M ▼ |
| Q1-2025 | $208.47M ▼ | $273.66M ▼ | $56.43M ▼ | $217.22M ▼ |
| Q4-2024 | $209.54M ▼ | $313.31M ▼ | $60.36M ▼ | $252.95M ▼ |
| Q3-2024 | $228.18M | $344.33M | $63.13M | $281.2M |
What's financially strong about this company?
Most assets are in cash and investments, with no risky goodwill or intangibles. Debt is low and mostly long-term, and the company can easily cover its bills in the near term.
What are the financial risks or weaknesses?
Cash and investments are dropping quickly, and the company has a long history of losses. If this trend continues, they may need to raise more money, which could dilute shareholders.
Cash Flow Statement
| Period | Net Income | Cash From Operations | Cash From Investing | Cash From Financing | Net Change | Free Cash Flow |
|---|---|---|---|---|---|---|
| Q3-2025 | $-27.55M ▲ | $-25.18M ▲ | $10.85M ▼ | $277K ▲ | $-14.06M ▼ | $-25.3M ▲ |
| Q2-2025 | $-54.1M ▼ | $-28.26M ▲ | $24.04M ▼ | $6K ▼ | $-4.22M ▼ | $-28.68M ▲ |
| Q1-2025 | $-39.99M ▼ | $-36.73M ▼ | $49.38M ▲ | $468K ▼ | $13.12M ▲ | $-37.77M ▼ |
| Q4-2024 | $-35.49M ▼ | $-35.47M ▼ | $15.93M ▼ | $3.86M ▲ | $-15.68M ▼ | $-35.99M ▼ |
| Q3-2024 | $-34.68M | $-32.66M | $26.52M | $244K | $-5.9M | $-33.33M |
What's strong about this company's cash flow?
Losses and cash burn are shrinking compared to last quarter, showing some improvement. Capital spending is very low, so most cash goes to running the business.
What are the cash flow concerns?
The company is burning through cash with no sign of self-sufficiency, and the cash balance is running dangerously low. It will need to raise more money soon to survive.
Revenue by Products
| Product | Q1-2025 | Q2-2025 | Q3-2025 |
|---|---|---|---|
Reportable Segment | $0 ▲ | $0 ▲ | $0 ▲ |
Revenue by Geography
| Region | Q4-2024 | Q1-2025 | Q2-2025 | Q3-2025 |
|---|---|---|---|---|
NonUS | $0 ▲ | $0 ▲ | $0 ▲ | $0 ▲ |
UNITED STATES | $10.00M ▲ | $0 ▼ | $0 ▲ | $0 ▲ |
5-Year Trend Analysis
A comprehensive look at Caribou Biosciences, Inc.'s financial evolution and strategic trajectory over the past five years.
Caribou’s main strengths lie in its cutting-edge gene-editing technology, strong scientific foundation, and focused pipeline of differentiated allogeneic CAR‑T therapies. It has built a meaningful patent estate, attracted high-profile scientific leadership, and secured validation through industry partnerships. Financially, it still maintains a positive equity base and a liquidity position that, while declining, remains stronger than many early-stage peers. These factors support its ability to pursue ambitious innovation in a high-potential field.
The company faces significant risks on multiple fronts. Its income statement shows rapidly expanding losses and no line of sight yet to profitability, while its cash flow profile reflects accelerating burn and growing dependence on external capital. The balance sheet, though currently adequate, is weakening as cash is consumed and net debt emerges. Overlaying this are the usual biotech hazards: clinical failure, regulatory setbacks, intense competition, and the potential difficulty of raising additional funds if market sentiment or trial data turn unfavorable.
The outlook for Caribou is highly dependent on the success of its lead programs and its ability to manage cash prudently. If CB‑010 and CB‑011 deliver strong and durable clinical results, the company could move toward pivotal trials, attract new partnerships, and improve its financing options, potentially transforming its financial profile over time. If results are disappointing or delayed, the combination of rising losses and shrinking liquidity could become more problematic. Overall, the story is one of high scientific promise paired with substantial financial and execution risk, typical of a clinical-stage biotech at a critical inflection point.

CEO
Rachel E. Haurwitz
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(Year 2024)
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Rating : C
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