CRL
CRL
Charles River Laboratories International, Inc.Income Statement
| Period | Revenue | Operating Expense | Net Income | Net Profit Margin | Earnings Per Share | EBITDA |
|---|---|---|---|---|---|---|
| Q4-2025 | $994.23M ▼ | $187.63M ▼ | $-276.56M ▼ | -27.82% ▼ | $-5.62 ▼ | $198.5M ▲ |
| Q3-2025 | $1B ▼ | $204.99M ▼ | $54.42M ▲ | 5.42% ▲ | $1.11 ▲ | $197.77M ▼ |
| Q2-2025 | $1.03B ▲ | $256.93M ▲ | $52.33M ▲ | 5.07% ▲ | $1.06 ▲ | $220.89M ▲ |
| Q1-2025 | $984.17M ▼ | $243.06M ▼ | $25.47M ▲ | 2.59% ▲ | $0.5 ▲ | $184.23M ▲ |
| Q4-2024 | $1B | $451.93M | $-215.7M | -21.52% | $-4.22 | $-86.45M |
What's going well?
Revenue stayed fairly steady and the core business remains profitable at the operating level. The company managed to cut some overhead costs this quarter.
What's concerning?
A massive one-time expense wiped out profits, leading to a large net loss. Margins are under pressure, and even without the unusual charge, profitability is slipping.
Balance Statement
| Period | Cash & Short-term | Total Assets | Total Liabilities | Total Equity |
|---|---|---|---|---|
| Q4-2025 | $213.77M ▲ | $7.14B ▼ | $3.92B ▼ | $3.16B ▼ |
| Q3-2025 | $207.67M ▲ | $7.51B ▼ | $4.06B ▼ | $3.41B ▲ |
| Q2-2025 | $182.82M ▼ | $7.56B ▼ | $4.16B ▼ | $3.35B ▲ |
| Q1-2025 | $229.36M ▲ | $7.58B ▲ | $4.34B ▲ | $3.19B ▼ |
| Q4-2024 | $194.61M | $7.53B | $4.02B | $3.46B |
What's financially strong about this company?
The company has a solid base of physical assets and positive equity. Customers are prepaying for services, and inventory and receivables are being managed well.
What are the financial risks or weaknesses?
Debt is rising quickly, cash is low, and nearly half the assets are goodwill and intangibles that could lose value. Book value is falling, and the company has little room for error if business slows.
Cash Flow Statement
| Period | Net Income | Cash From Operations | Cash From Investing | Cash From Financing | Net Change | Free Cash Flow |
|---|---|---|---|---|---|---|
| Q4-2025 | $-276.56M ▼ | $147.52M ▼ | $-73.67M ▼ | $-51.86M ▲ | $6.77M ▼ | $58.57M ▼ |
| Q3-2025 | $55.56M ▲ | $213.83M ▲ | $-33.7M ▲ | $-152.62M ▲ | $24.48M ▲ | $178.25M ▲ |
| Q2-2025 | $52.69M ▲ | $204.6M ▲ | $-37.34M ▲ | $-226.92M ▼ | $-46.99M ▼ | $169.31M ▲ |
| Q1-2025 | $25.88M ▲ | $171.7M ▲ | $-45.48M ▲ | $-105.33M ▼ | $26.16M ▲ | $112.37M ▲ |
| Q4-2024 | $-213.75M | $159.36M | $-76.1M | $-75.88M | $-6.07M | $83.75M |
What's strong about this company's cash flow?
The company continues to generate positive operating cash flow and free cash flow, even during a quarter with a big accounting loss. Debt is being paid down, and there is no reliance on outside funding.
What are the cash flow concerns?
Operating and free cash flow dropped sharply, and the company posted a large net loss. Higher capital spending and paying down suppliers could pressure cash if trends continue.
Revenue by Products
| Product | Q1-2025 | Q2-2025 | Q3-2025 | Q4-2025 |
|---|---|---|---|---|
Discovery and Safety Assessment | $590.00M ▲ | $620.00M ▲ | $600.00M ▼ | $590.00M ▼ |
Manufacturing Support | $180.00M ▲ | $200.00M ▲ | $190.00M ▼ | $200.00M ▲ |
Research Models and Services | $210.00M ▲ | $210.00M ▲ | $210.00M ▲ | $210.00M ▲ |
Revenue by Geography
| Region | Q1-2025 | Q2-2025 | Q3-2025 | Q4-2025 |
|---|---|---|---|---|
Asia Pacific | $40.00M ▲ | $50.00M ▲ | $50.00M ▲ | $60.00M ▲ |
CANADA | $130.00M ▲ | $140.00M ▲ | $120.00M ▼ | $120.00M ▲ |
Europe | $260.00M ▲ | $280.00M ▲ | $280.00M ▲ | $280.00M ▲ |
UNITED STATES | $540.00M ▲ | $550.00M ▲ | $540.00M ▼ | $520.00M ▼ |
Q4 2025 Earnings Call Summary
Read Call Summary5-Year Trend Analysis
A comprehensive look at Charles River Laboratories International, Inc.'s financial evolution and strategic trajectory over the past five years.
Key strengths include a leading position in the preclinical CRO market, a highly integrated and global service offering, strong historical margins, and consistently solid operating and free cash flow. The company’s digital and AI platforms, specialized research models, and expanding capabilities in cell and gene therapy further differentiate it. A gradually improving leverage profile and adequate liquidity provide some balance sheet resilience.
Major risks stem from the sharp recent deterioration in profitability, including negative earnings and a collapse in EBITDA, which raise questions about cost structure, pricing, and potential one‑off charges or impairments. Ongoing reliance on goodwill and intangible assets, combined with still‑meaningful debt, adds financial and accounting risk if performance remains weak. Competitive and regulatory pressures, shifting biotech funding, and the need to keep pace with rapid technological change also pose strategic challenges.
The outlook is mixed: underlying demand and cash generation appear relatively healthy, and the company has a strong competitive and technological foundation, but the recent income statement damage cannot be ignored. Future performance will hinge on whether management can restore sustainable margins, continue deleveraging, and fully capitalize on its innovation platforms and growth areas like cell and gene therapy. Until the causes of the recent profit downturn are clarified and addressed, the trajectory remains uncertain, albeit with meaningful upside potential if execution improves.
About Charles River Laboratories International, Inc.
https://www.criver.comCharles River Laboratories International, Inc., a non-clinical contract research organization, provides drug discovery, non-clinical development, and safety testing services in the United States, Europe, Canada, the Asia Pacific, and internationally.
Income Statement
| Period | Revenue | Operating Expense | Net Income | Net Profit Margin | Earnings Per Share | EBITDA |
|---|---|---|---|---|---|---|
| Q4-2025 | $994.23M ▼ | $187.63M ▼ | $-276.56M ▼ | -27.82% ▼ | $-5.62 ▼ | $198.5M ▲ |
| Q3-2025 | $1B ▼ | $204.99M ▼ | $54.42M ▲ | 5.42% ▲ | $1.11 ▲ | $197.77M ▼ |
| Q2-2025 | $1.03B ▲ | $256.93M ▲ | $52.33M ▲ | 5.07% ▲ | $1.06 ▲ | $220.89M ▲ |
| Q1-2025 | $984.17M ▼ | $243.06M ▼ | $25.47M ▲ | 2.59% ▲ | $0.5 ▲ | $184.23M ▲ |
| Q4-2024 | $1B | $451.93M | $-215.7M | -21.52% | $-4.22 | $-86.45M |
What's going well?
Revenue stayed fairly steady and the core business remains profitable at the operating level. The company managed to cut some overhead costs this quarter.
What's concerning?
A massive one-time expense wiped out profits, leading to a large net loss. Margins are under pressure, and even without the unusual charge, profitability is slipping.
Balance Statement
| Period | Cash & Short-term | Total Assets | Total Liabilities | Total Equity |
|---|---|---|---|---|
| Q4-2025 | $213.77M ▲ | $7.14B ▼ | $3.92B ▼ | $3.16B ▼ |
| Q3-2025 | $207.67M ▲ | $7.51B ▼ | $4.06B ▼ | $3.41B ▲ |
| Q2-2025 | $182.82M ▼ | $7.56B ▼ | $4.16B ▼ | $3.35B ▲ |
| Q1-2025 | $229.36M ▲ | $7.58B ▲ | $4.34B ▲ | $3.19B ▼ |
| Q4-2024 | $194.61M | $7.53B | $4.02B | $3.46B |
What's financially strong about this company?
The company has a solid base of physical assets and positive equity. Customers are prepaying for services, and inventory and receivables are being managed well.
What are the financial risks or weaknesses?
Debt is rising quickly, cash is low, and nearly half the assets are goodwill and intangibles that could lose value. Book value is falling, and the company has little room for error if business slows.
Cash Flow Statement
| Period | Net Income | Cash From Operations | Cash From Investing | Cash From Financing | Net Change | Free Cash Flow |
|---|---|---|---|---|---|---|
| Q4-2025 | $-276.56M ▼ | $147.52M ▼ | $-73.67M ▼ | $-51.86M ▲ | $6.77M ▼ | $58.57M ▼ |
| Q3-2025 | $55.56M ▲ | $213.83M ▲ | $-33.7M ▲ | $-152.62M ▲ | $24.48M ▲ | $178.25M ▲ |
| Q2-2025 | $52.69M ▲ | $204.6M ▲ | $-37.34M ▲ | $-226.92M ▼ | $-46.99M ▼ | $169.31M ▲ |
| Q1-2025 | $25.88M ▲ | $171.7M ▲ | $-45.48M ▲ | $-105.33M ▼ | $26.16M ▲ | $112.37M ▲ |
| Q4-2024 | $-213.75M | $159.36M | $-76.1M | $-75.88M | $-6.07M | $83.75M |
What's strong about this company's cash flow?
The company continues to generate positive operating cash flow and free cash flow, even during a quarter with a big accounting loss. Debt is being paid down, and there is no reliance on outside funding.
What are the cash flow concerns?
Operating and free cash flow dropped sharply, and the company posted a large net loss. Higher capital spending and paying down suppliers could pressure cash if trends continue.
Revenue by Products
| Product | Q1-2025 | Q2-2025 | Q3-2025 | Q4-2025 |
|---|---|---|---|---|
Discovery and Safety Assessment | $590.00M ▲ | $620.00M ▲ | $600.00M ▼ | $590.00M ▼ |
Manufacturing Support | $180.00M ▲ | $200.00M ▲ | $190.00M ▼ | $200.00M ▲ |
Research Models and Services | $210.00M ▲ | $210.00M ▲ | $210.00M ▲ | $210.00M ▲ |
Revenue by Geography
| Region | Q1-2025 | Q2-2025 | Q3-2025 | Q4-2025 |
|---|---|---|---|---|
Asia Pacific | $40.00M ▲ | $50.00M ▲ | $50.00M ▲ | $60.00M ▲ |
CANADA | $130.00M ▲ | $140.00M ▲ | $120.00M ▼ | $120.00M ▲ |
Europe | $260.00M ▲ | $280.00M ▲ | $280.00M ▲ | $280.00M ▲ |
UNITED STATES | $540.00M ▲ | $550.00M ▲ | $540.00M ▼ | $520.00M ▼ |
Q4 2025 Earnings Call Summary
Read Call Summary5-Year Trend Analysis
A comprehensive look at Charles River Laboratories International, Inc.'s financial evolution and strategic trajectory over the past five years.
Key strengths include a leading position in the preclinical CRO market, a highly integrated and global service offering, strong historical margins, and consistently solid operating and free cash flow. The company’s digital and AI platforms, specialized research models, and expanding capabilities in cell and gene therapy further differentiate it. A gradually improving leverage profile and adequate liquidity provide some balance sheet resilience.
Major risks stem from the sharp recent deterioration in profitability, including negative earnings and a collapse in EBITDA, which raise questions about cost structure, pricing, and potential one‑off charges or impairments. Ongoing reliance on goodwill and intangible assets, combined with still‑meaningful debt, adds financial and accounting risk if performance remains weak. Competitive and regulatory pressures, shifting biotech funding, and the need to keep pace with rapid technological change also pose strategic challenges.
The outlook is mixed: underlying demand and cash generation appear relatively healthy, and the company has a strong competitive and technological foundation, but the recent income statement damage cannot be ignored. Future performance will hinge on whether management can restore sustainable margins, continue deleveraging, and fully capitalize on its innovation platforms and growth areas like cell and gene therapy. Until the causes of the recent profit downturn are clarified and addressed, the trajectory remains uncertain, albeit with meaningful upside potential if execution improves.

CEO
James C. Foster
Compensation Summary
(Year 2023)
Upcoming Earnings
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Ratings Snapshot
Rating : C-
Most Recent Analyst Grades
UBS
Neutral
TD Cowen
Buy
Mizuho
Neutral
Evercore ISI Group
Outperform
Barclays
Overweight
Citigroup
Buy
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