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Charles River Laboratories International, Inc.

CRL

Charles River Laboratories International, Inc. NYSE
$178.49 1.73% (+3.03)

Market Cap $8.78 B
52w High $228.88
52w Low $91.86
P/E -115.90
Volume 932.00K
Outstanding Shares 49.22M

Income Statement

Period Revenue Operating Expense Net Income Net Profit Margin Earnings Per Share EBITDA
Q4-2025 $994.23M $187.63M $-276.56M -27.82% $-5.62 $198.5M
Q3-2025 $1B $204.99M $54.42M 5.42% $1.11 $197.77M
Q2-2025 $1.03B $256.93M $52.33M 5.07% $1.06 $220.89M
Q1-2025 $984.17M $243.06M $25.47M 2.59% $0.5 $184.23M
Q4-2024 $1B $451.93M $-215.7M -21.52% $-4.22 $-86.45M

What's going well?

Revenue stayed fairly steady and the core business remains profitable at the operating level. The company managed to cut some overhead costs this quarter.

What's concerning?

A massive one-time expense wiped out profits, leading to a large net loss. Margins are under pressure, and even without the unusual charge, profitability is slipping.

Balance Statement

Period Cash & Short-term Total Assets Total Liabilities Total Equity
Q4-2025 $213.77M $7.14B $3.92B $3.16B
Q3-2025 $207.67M $7.51B $4.06B $3.41B
Q2-2025 $182.82M $7.56B $4.16B $3.35B
Q1-2025 $229.36M $7.58B $4.34B $3.19B
Q4-2024 $194.61M $7.53B $4.02B $3.46B

What's financially strong about this company?

The company has a solid base of physical assets and positive equity. Customers are prepaying for services, and inventory and receivables are being managed well.

What are the financial risks or weaknesses?

Debt is rising quickly, cash is low, and nearly half the assets are goodwill and intangibles that could lose value. Book value is falling, and the company has little room for error if business slows.

Cash Flow Statement

Period Net Income Cash From Operations Cash From Investing Cash From Financing Net Change Free Cash Flow
Q4-2025 $-276.56M $147.52M $-73.67M $-51.86M $6.77M $58.57M
Q3-2025 $55.56M $213.83M $-33.7M $-152.62M $24.48M $178.25M
Q2-2025 $52.69M $204.6M $-37.34M $-226.92M $-46.99M $169.31M
Q1-2025 $25.88M $171.7M $-45.48M $-105.33M $26.16M $112.37M
Q4-2024 $-213.75M $159.36M $-76.1M $-75.88M $-6.07M $83.75M

What's strong about this company's cash flow?

The company continues to generate positive operating cash flow and free cash flow, even during a quarter with a big accounting loss. Debt is being paid down, and there is no reliance on outside funding.

What are the cash flow concerns?

Operating and free cash flow dropped sharply, and the company posted a large net loss. Higher capital spending and paying down suppliers could pressure cash if trends continue.

Revenue by Products

Product Q1-2025Q2-2025Q3-2025Q4-2025
Discovery and Safety Assessment
Discovery and Safety Assessment
$590.00M $620.00M $600.00M $590.00M
Manufacturing Support
Manufacturing Support
$180.00M $200.00M $190.00M $200.00M
Research Models and Services
Research Models and Services
$210.00M $210.00M $210.00M $210.00M

Revenue by Geography

Region Q1-2025Q2-2025Q3-2025Q4-2025
Asia Pacific
Asia Pacific
$40.00M $50.00M $50.00M $60.00M
CANADA
CANADA
$130.00M $140.00M $120.00M $120.00M
Europe
Europe
$260.00M $280.00M $280.00M $280.00M
UNITED STATES
UNITED STATES
$540.00M $550.00M $540.00M $520.00M

Q4 2025 Earnings Call Summary

Read Call Summary

5-Year Trend Analysis

A comprehensive look at Charles River Laboratories International, Inc.'s financial evolution and strategic trajectory over the past five years.

+ Strengths

Key strengths include a leading position in the preclinical CRO market, a highly integrated and global service offering, strong historical margins, and consistently solid operating and free cash flow. The company’s digital and AI platforms, specialized research models, and expanding capabilities in cell and gene therapy further differentiate it. A gradually improving leverage profile and adequate liquidity provide some balance sheet resilience.

! Risks

Major risks stem from the sharp recent deterioration in profitability, including negative earnings and a collapse in EBITDA, which raise questions about cost structure, pricing, and potential one‑off charges or impairments. Ongoing reliance on goodwill and intangible assets, combined with still‑meaningful debt, adds financial and accounting risk if performance remains weak. Competitive and regulatory pressures, shifting biotech funding, and the need to keep pace with rapid technological change also pose strategic challenges.

Outlook

The outlook is mixed: underlying demand and cash generation appear relatively healthy, and the company has a strong competitive and technological foundation, but the recent income statement damage cannot be ignored. Future performance will hinge on whether management can restore sustainable margins, continue deleveraging, and fully capitalize on its innovation platforms and growth areas like cell and gene therapy. Until the causes of the recent profit downturn are clarified and addressed, the trajectory remains uncertain, albeit with meaningful upside potential if execution improves.