GPCR
GPCR
Structure Therapeutics Inc.Income Statement
| Period | Revenue | Operating Expense | Net Income | Net Profit Margin | Earnings Per Share | EBITDA |
|---|---|---|---|---|---|---|
| Q4-2025 | $0 | $-23.99M ▼ | $33M ▲ | 0% | $0.6 ▲ | $33.59M ▲ |
| Q3-2025 | $0 | $73.79M ▲ | $-65.71M ▼ | 0% | $-1.11 ▼ | $-65.31M ▲ |
| Q2-2025 | $0 | $70.45M ▲ | $-61.66M ▼ | 0% | $-1.08 ▼ | $-70.16M ▼ |
| Q1-2025 | $0 | $56.31M ▲ | $-46.83M ▼ | 0% | $-0.81 ▼ | $-56.04M ▼ |
| Q4-2024 | $0 | $47.06M | $-36.48M | 0% | $-0.63 | $-46.79M |
Balance Statement
| Period | Cash & Short-term | Total Assets | Total Liabilities | Total Equity |
|---|---|---|---|---|
| Q4-2025 | $1.45B ▲ | $1.58B ▲ | $67.54M ▲ | $1.52B ▲ |
| Q3-2025 | $799.04M ▲ | $832.16M ▲ | $62.14M ▲ | $770.02M ▼ |
| Q2-2025 | $786.5M ▼ | $816.44M ▼ | $44.36M ▲ | $772.08M ▼ |
| Q1-2025 | $836.88M ▼ | $866.55M ▼ | $41.91M ▲ | $824.64M ▼ |
| Q4-2024 | $883.52M | $903.33M | $38.49M | $864.84M |
Cash Flow Statement
| Period | Net Income | Cash From Operations | Cash From Investing | Cash From Financing | Net Change | Free Cash Flow |
|---|---|---|---|---|---|---|
| Q4-2025 | $33M ▲ | $-64.42M ▼ | $56.14M ▲ | $704.99M ▲ | $0 ▲ | $-65.91M ▼ |
| Q3-2025 | $-65.71M ▼ | $-51M ▲ | $-49.32M ▼ | $56.2M ▲ | $-44.11M ▼ | $-52.57M ▲ |
| Q2-2025 | $-61.66M ▼ | $-54.56M ▼ | $48.94M ▲ | $517K ▼ | $-5.1M ▲ | $-54.79M ▼ |
| Q1-2025 | $-46.83M ▼ | $-52.23M ▼ | $34.03M ▲ | $809K ▲ | $-17.39M ▼ | $-52.54M ▼ |
| Q4-2024 | $-36.48M | $-36.47M | $33.23M | $615K | $-2.62M | $-36.48M |
5-Year Trend Analysis
A comprehensive look at Structure Therapeutics Inc.'s financial evolution and strategic trajectory over the past five years.
Key strengths include a very strong cash and liquidity position, minimal debt, and a clean balance sheet that supports several years of R&D. Scientifically, GPCR has a focused but diversified pipeline of oral small‑molecule therapies in a huge and growing metabolic disease market, underpinned by a modern structure‑based drug design platform. Early clinical data for the lead GLP‑1 candidate look promising, and the company has already attracted a notable licensing partner, which validates aspects of its technology and IP.
The largest risks stem from its stage of development and therapeutic focus. The company has no product revenue, deep operating and cash losses, and depends on external capital and partnership income. Clinical risk is substantial: setbacks in Phase 3 for the lead obesity program, or unfavorable comparisons versus incumbents, could significantly impair long‑term prospects. Competitive intensity from large pharma, potential safety or tolerability issues that emerge in larger populations, and future reimbursement and pricing challenges add further uncertainty.
The outlook is that of a high‑potential, high‑uncertainty clinical‑stage biotech. Financially, the company appears well‑funded to pursue its near‑ to medium‑term clinical goals, reducing immediate dilution and liquidity concerns. Strategically, success hinges on translating strong mid‑stage results into pivotal trial success and carving out a compelling position in an increasingly crowded oral obesity market. If the science and execution hold, GPCR could evolve into a meaningful player in metabolic disease; if not, its lack of diversification into revenue‑generating assets amplifies downside risks. Overall, future performance will be driven far more by clinical and regulatory outcomes than by current financial ratios.
About Structure Therapeutics Inc.
https://structuretx.comStructure Therapeutics Inc., a clinical stage global biopharmaceutical company, develops and delivers novel oral therapeutics to treat a range of chronic diseases with unmet medical needs.
Income Statement
| Period | Revenue | Operating Expense | Net Income | Net Profit Margin | Earnings Per Share | EBITDA |
|---|---|---|---|---|---|---|
| Q4-2025 | $0 | $-23.99M ▼ | $33M ▲ | 0% | $0.6 ▲ | $33.59M ▲ |
| Q3-2025 | $0 | $73.79M ▲ | $-65.71M ▼ | 0% | $-1.11 ▼ | $-65.31M ▲ |
| Q2-2025 | $0 | $70.45M ▲ | $-61.66M ▼ | 0% | $-1.08 ▼ | $-70.16M ▼ |
| Q1-2025 | $0 | $56.31M ▲ | $-46.83M ▼ | 0% | $-0.81 ▼ | $-56.04M ▼ |
| Q4-2024 | $0 | $47.06M | $-36.48M | 0% | $-0.63 | $-46.79M |
Balance Statement
| Period | Cash & Short-term | Total Assets | Total Liabilities | Total Equity |
|---|---|---|---|---|
| Q4-2025 | $1.45B ▲ | $1.58B ▲ | $67.54M ▲ | $1.52B ▲ |
| Q3-2025 | $799.04M ▲ | $832.16M ▲ | $62.14M ▲ | $770.02M ▼ |
| Q2-2025 | $786.5M ▼ | $816.44M ▼ | $44.36M ▲ | $772.08M ▼ |
| Q1-2025 | $836.88M ▼ | $866.55M ▼ | $41.91M ▲ | $824.64M ▼ |
| Q4-2024 | $883.52M | $903.33M | $38.49M | $864.84M |
Cash Flow Statement
| Period | Net Income | Cash From Operations | Cash From Investing | Cash From Financing | Net Change | Free Cash Flow |
|---|---|---|---|---|---|---|
| Q4-2025 | $33M ▲ | $-64.42M ▼ | $56.14M ▲ | $704.99M ▲ | $0 ▲ | $-65.91M ▼ |
| Q3-2025 | $-65.71M ▼ | $-51M ▲ | $-49.32M ▼ | $56.2M ▲ | $-44.11M ▼ | $-52.57M ▲ |
| Q2-2025 | $-61.66M ▼ | $-54.56M ▼ | $48.94M ▲ | $517K ▼ | $-5.1M ▲ | $-54.79M ▼ |
| Q1-2025 | $-46.83M ▼ | $-52.23M ▼ | $34.03M ▲ | $809K ▲ | $-17.39M ▼ | $-52.54M ▼ |
| Q4-2024 | $-36.48M | $-36.47M | $33.23M | $615K | $-2.62M | $-36.48M |
5-Year Trend Analysis
A comprehensive look at Structure Therapeutics Inc.'s financial evolution and strategic trajectory over the past five years.
Key strengths include a very strong cash and liquidity position, minimal debt, and a clean balance sheet that supports several years of R&D. Scientifically, GPCR has a focused but diversified pipeline of oral small‑molecule therapies in a huge and growing metabolic disease market, underpinned by a modern structure‑based drug design platform. Early clinical data for the lead GLP‑1 candidate look promising, and the company has already attracted a notable licensing partner, which validates aspects of its technology and IP.
The largest risks stem from its stage of development and therapeutic focus. The company has no product revenue, deep operating and cash losses, and depends on external capital and partnership income. Clinical risk is substantial: setbacks in Phase 3 for the lead obesity program, or unfavorable comparisons versus incumbents, could significantly impair long‑term prospects. Competitive intensity from large pharma, potential safety or tolerability issues that emerge in larger populations, and future reimbursement and pricing challenges add further uncertainty.
The outlook is that of a high‑potential, high‑uncertainty clinical‑stage biotech. Financially, the company appears well‑funded to pursue its near‑ to medium‑term clinical goals, reducing immediate dilution and liquidity concerns. Strategically, success hinges on translating strong mid‑stage results into pivotal trial success and carving out a compelling position in an increasingly crowded oral obesity market. If the science and execution hold, GPCR could evolve into a meaningful player in metabolic disease; if not, its lack of diversification into revenue‑generating assets amplifies downside risks. Overall, future performance will be driven far more by clinical and regulatory outcomes than by current financial ratios.

CEO
Raymond C. Stevens
Compensation Summary
(Year 2024)
Upcoming Earnings
ETFs Holding This Stock
Summary
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Ratings Snapshot
Rating : C+
Most Recent Analyst Grades
Price Target
Institutional Ownership
FMR LLC
Shares:8.71M
Value:$548.7M
WELLINGTON MANAGEMENT GROUP LLP
Shares:7.12M
Value:$448.54M
AVORO CAPITAL ADVISORS LLC
Shares:6.56M
Value:$412.87M
Summary
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