Stock Taper
KPTI
KARYOPHARM THERAPEUTICS INC.
NASDAQ
$0.67
▼ DOWN 16.42% (-0.13)

KEY STATISTICS

Market Cap$15.35 M
52w High$10.99
52w Low$0.63
Dividend Yield—
Frequency—
P/E-0.05
Volume1.98M
Shares Out.22.66M

COMPANY

LEADERSHIP

Richard A. Paulson
CHIEF EXECUTIVE
Richard A. Paulson

COMPENSATION 2026

Salary$770,000
Stock Awards$838,996
Incentive Plan Pay$350,350
All Other Comp.$19,912
Total$2,320,902

ABOUT

SECTOR
Healthcare
WENT PUBLIC
November 6, 2013
METHOD OF GOING PUBLIC
IPO
FULL TIME EMPLOYEES
228

PRICE TARGET

Target High$16.00
Target Low$3.00
Target Median$9.50
Target Consensus$9.50

UPCOMING EARNINGS

DateNov 2, 2026
DayMonday
Rev. Est.$33.54M
NOV
2
MON

SPLIT RECORD

DATETYPERATIO
2025-02-26Reverse1:15

ETFS HOLDING THIS STOCK

ETFS HOLDING
55
LISTED HERE
10
RANKED BY POSITION SIZE

INSTITUTIONAL OWNERSHIP

SHARES OWNED
70.48%
HOLDERS
130
TOP 8 OF 130 · RANKED BY POSITION SIZE

PRICE

$0.67 ▼ DOWN 16.42% (−$0.13)
OVERLAYS
$0.67$0.759:30 AM10:35 AM11:40 AM12:44 PM1:49 PM2:54 PM3:59 PM0.67

About Karyopharm Therapeutics Inc.

https://www.karyopharm.com ↗

Karyopharm Therapeutics develops and commercializes SINE compounds targeting nuclear export, with lead drug XPOVIO for multiple myeloma and lymphoma, licensed in Europe and Latin America, focusing on cancer treatments.

INDUSTRY

Biotechnology

A PRODUCT KARYOPHARM THERAPEUTICS INC. IS KNOWN FOR

XPOVIO® (selinexor)
XPOVIO® (selinexor)

XPOVIO® is an oral cancer treatment approved for multiple myeloma and relapsed/refractory diffuse large B-cell lymphoma, serving as Karyopharm's flagship product focused on targeting cancer's fundamental mechanisms.

Karyopharm Therapeutics in 2025

SENTIMENT: + POSITIVE
Lori Macomber
OTHER · OCTOBER 2025

Karyopharm Secures $100 Million in Strategic Financing, Extending Cash Runway Beyond Key 2026 Clinical Trial Readouts

Karyopharm Therapeutics announced comprehensive financing and capital structure transactions providing the company with $100 million in financial flexibility and additional capital. This strategic move extends the company's cash runway into the second quarter of 2026, a critical development as it de-risks the company's financial position ahead of the highly anticipated top-line data from its pivotal Phase 3 SENTRY trial in myelofibrosis.

RESTRUCTURING · JULY 11, 2025 · IN PROGRESS

Karyopharm Therapeutics Announces 20% Workforce Reduction and Explores Strategic Alternatives Amid Financial Pressures

In a significant strategic move to preserve capital, Karyopharm Therapeutics announced a restructuring that includes a 20% reduction of its workforce. This decision is part of a broader, board-led review of strategic and financing options, which could include a merger, sale of the company, or other transactions, as it faces a cash crunch and upcoming debt maturities.

Latest News

PRNEWSWIRE · OCT 1, 2026

Karyopharm Therapeutics Reports Inducement Grant Under Nasdaq Listing Rule 5635(c)(4)

NEWTON, Mass., Oct. 1, 2026 /PRNewswire/ -- Karyopharm Therapeutics Inc. (Nasdaq: KPTI), a commercial-stage pharmaceutical company pioneering novel cancer therapies, today announced that the Company granted 333 restricted stock units (RSUs) to one newly-hired employee.

EARLIER COVERAGE
DEFENSE WORLD · SEP 30, 2026

Reviewing Alpha Cognition (NASDAQ:ACOG) & Karyopharm Therapeutics (NASDAQ:KPTI)

Karyopharm Therapeutics (NASDAQ: KPTI - Get Free Report) and Alpha Cognition (NASDAQ: ACOG - Get Free Report) are both small-cap healthcare companies, but which is the better business? We will contrast the two companies based on the strength of their institutional ownership, earnings, valuation, profitability, dividends, risk and analyst recommendations. Analyst Ratings This is a breakdown of

RATINGS SNAPSHOT

Overall rating: B-

DCFROEROAD/EP/EP/B
Discounted Cash Flow5
Return On Equity5
Return On Assets1
Debt To Equity1
Price To Earnings1
Price To Book1
Overall Score2

MOST RECENT ANALYST GRADES

GRADE SUMMARY
OUTPERFORM 2
NEUTRAL 1
OVERWEIGHT 1
4 GRADES IN THE LAST 12 MONTHS

SECTORS PEERS

PEERPRICE
XFOR$2.90COMPARE
TELO$1.25COMPARE
INMB$1.94COMPARE
ALGS$5.57COMPARE
MDCX$0.17COMPARE
SNTI$0.34COMPARE

INSIDER TRADES

★
OFFICER: CHIEF ACCOUNTING OFFICER
Abate Kristin
Sale · 378 shares
2026-10-01
★
OFFICER: CHIEF ACCOUNTING OFFICER
Abate Kristin
Sale · 19 shares
2026-09-01
★
OFFICER: EVP, CHIEF DEVELOPMENT OFFICER
Poulton Stuart
Sale · 189 shares
2026-07-28
★
DIRECTOR
Greene Barry E
Purchase · 15.5K shares
2026-05-21