MAZE - Maze Therapeutics,... Stock Analysis | Stock Taper
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Maze Therapeutics, Inc.

MAZE

Maze Therapeutics, Inc. NASDAQ
$26.80 -0.19% (-0.05)

Market Cap $1.33 B
52w High $53.65
52w Low $7.16
P/E -8.79
Volume 852.28K
Outstanding Shares 49.71M

Income Statement

Period Revenue Operating Expense Net Income Net Profit Margin Earnings Per Share EBITDA
Q4-2025 $0 $37.56M $-34.57M 0% $-0.87 $-37.56M
Q3-2025 $0 $32.97M $-30.09M 0% $-0.66 $-29.52M
Q2-2025 $0 $35.83M $-33.68M 0% $-0.77 $-33.03M
Q1-2025 $0 $35.4M $-32.79M 0% $-0.75 $-34.72M
Q4-2024 $0 $29.73M $-29.58M 0% $-0.11 $-29.02M

Balance Statement

Period Cash & Short-term Total Assets Total Liabilities Total Equity
Q4-2025 $341.92M $397.13M $42.16M $354.97M
Q3-2025 $383.94M $422.06M $42.62M $379.44M
Q2-2025 $264.54M $303.52M $41.28M $262.24M
Q1-2025 $294.37M $332.84M $40.77M $292.07M
Q4-2024 $196.81M $240.54M $43.64M $196.9M

Cash Flow Statement

Period Net Income Cash From Operations Cash From Investing Cash From Financing Net Change Free Cash Flow
Q4-2025 $-34.57M $-27.73M $-103.39M $3.59M $-127.53M $-27.76M
Q3-2025 $-30.09M $-24.64M $-66.88M $143.76M $52.23M $-24.71M
Q2-2025 $-33.68M $-30.05M $-393K $612K $-29.83M $-30.45M
Q1-2025 $-32.79M $-29.52M $-299K $127.38M $97.56M $-29.82M
Q4-2024 $-29.58M $-22.45M $-605K $70.26M $47.2M $-23.06M

5-Year Trend Analysis

A comprehensive look at Maze Therapeutics, Inc.'s financial evolution and strategic trajectory over the past five years.

+ Strengths

Maze combines a strong, cash‑rich balance sheet and very low debt with a focused, genetically driven R&D strategy. Its Compass platform creates a clear scientific narrative and a structured way to generate new drug candidates. The pipeline includes multiple programs in serious diseases with significant unmet needs, and existing partnerships provide external validation and some non‑dilutive funding. Operating costs are concentrated in R&D rather than bloated infrastructure, which aligns spending with the company’s core mission.

! Risks

At the same time, Maze has no revenue, substantial ongoing losses, and meaningful cash burn, with a track record of cumulative negative earnings. Each major asset carries typical biotech risks: clinical failure, safety concerns, regulatory setbacks, delays, and competition from better‑positioned rivals. The company will likely need additional capital over time, which could depend on market conditions and trial outcomes. Its prospects are also concentrated in a relatively small number of lead programs and in the continued success of the Compass platform, creating a high degree of binary risk around key milestones.

Outlook

In the near to medium term, Maze is likely to remain loss‑making and cash‑consuming while it advances its pipeline. The company’s future will be shaped primarily by clinical and regulatory milestones—especially for its APOL1 kidney program, dual‑use metabolic candidate, Pompe collaboration, and obesity efforts—along with its ability to maintain a healthy cash runway through partnerships and financings. If its genetics‑first approach continues to yield strong data, Maze could evolve into a partner of choice or a future commercial player in its chosen niches; if key programs disappoint, it may need to rethink its portfolio, cost base, or strategic focus. Uncertainty is high, which is typical for a company at this stage, and outcomes will hinge on scientific execution over the next several years.