MAZE
MAZE
Maze Therapeutics, Inc.Income Statement
| Period | Revenue | Operating Expense | Net Income | Net Profit Margin | Earnings Per Share | EBITDA |
|---|---|---|---|---|---|---|
| Q3-2025 | $0 | $32.97M ▼ | $-30.09M ▲ | 0% | $-0.66 ▲ | $-29.52M ▲ |
| Q2-2025 | $0 | $35.83M ▲ | $-33.68M ▼ | 0% | $-0.77 ▼ | $-33.03M ▲ |
| Q1-2025 | $0 | $35.4M ▲ | $-32.79M ▼ | 0% | $-0.75 ▼ | $-34.72M ▼ |
| Q4-2024 | $0 ▼ | $29.73M ▲ | $-29.58M ▼ | 0% ▲ | $-0.11 ▼ | $-29.02M ▼ |
| Q3-2024 | $2.5M | $26.73M | $-24.75M | -990.08% | $-0.06 | $-23.44M |
What's going well?
Maze managed to cut its operating expenses and reduce its net loss this quarter. The company also earned some interest income, which helped soften the losses.
What's concerning?
Maze still has no revenue, so it's burning cash with no sales in sight. The rising share count means existing shareholders are getting diluted while the company remains unprofitable.
Balance Statement
| Period | Cash & Short-term | Total Assets | Total Liabilities | Total Equity |
|---|---|---|---|---|
| Q3-2025 | $383.94M ▲ | $422.06M ▲ | $42.62M ▲ | $379.44M ▲ |
| Q2-2025 | $264.54M ▼ | $303.52M ▼ | $41.28M ▲ | $262.24M ▼ |
| Q1-2025 | $294.37M ▲ | $332.84M ▲ | $40.77M ▼ | $292.07M ▲ |
| Q4-2024 | $196.81M ▲ | $240.54M ▲ | $43.64M ▼ | $196.9M ▲ |
| Q3-2024 | $149.61M | $192.48M | $93.11M | $99.37M |
What's financially strong about this company?
MAZE is sitting on a massive cash pile, has almost no debt, and can easily pay all its bills. The asset base is high quality and liquid, with no risky goodwill or intangibles. Equity is strong and growing.
What are the financial risks or weaknesses?
The company has a history of losses, as shown by large negative retained earnings. There is little sign of customer prepayments or deferred revenue, and the business may not be generating profits yet.
Cash Flow Statement
| Period | Net Income | Cash From Operations | Cash From Investing | Cash From Financing | Net Change | Free Cash Flow |
|---|---|---|---|---|---|---|
| Q3-2025 | $-30.09M ▲ | $-24.64M ▲ | $-66.88M ▼ | $143.76M ▲ | $52.23M ▲ | $-24.71M ▲ |
| Q2-2025 | $-33.68M ▼ | $-30.05M ▼ | $-393K ▼ | $612K ▼ | $-29.83M ▼ | $-30.45M ▼ |
| Q1-2025 | $-32.79M ▼ | $-29.52M ▼ | $-299K ▲ | $127.38M ▲ | $97.56M ▲ | $-29.82M ▼ |
| Q4-2024 | $-29.58M ▼ | $-22.45M ▲ | $-605K ▼ | $70.26M ▲ | $47.2M ▲ | $-23.06M ▲ |
| Q3-2024 | $-24.75M | $-23.2M | $-103K | $-2.15M | $-25.46M | $-23.31M |
What's strong about this company's cash flow?
Cash burn is shrinking, and the company now has a much bigger cash cushion after raising funds. The current cash balance gives over three years of runway at the current burn rate.
What are the cash flow concerns?
The business is not generating cash from operations and is highly dependent on raising new money, mostly by issuing more shares and diluting existing owners. Most losses are real cash burn, not just accounting.
5-Year Trend Analysis
A comprehensive look at Maze Therapeutics, Inc.'s financial evolution and strategic trajectory over the past five years.
Maze has quickly evolved from a pre-revenue biotech into a company with meaningful revenue, positive earnings, and strong cash flow in its latest year. Its balance sheet is now cash-rich with low net debt, providing a substantial runway to fund research and trials. The Compass platform offers a distinctive scientific edge, and the pipeline features multiple genetically validated drug candidates, one of which has already been licensed to a global partner. Together, these elements suggest a business with growing financial flexibility and a credible scientific foundation.
Key risks center on the early and concentrated nature of the business. Profitability and cash flow have improved, but largely on the back of a single standout year tied to a major licensing deal, not yet a diversified revenue base. The company still shows a large accumulated deficit and a limited track record of sustained profitability. Clinical and regulatory setbacks in its lead programs or underperformance by partners could materially affect both its financials and strategic position. Competition from larger biopharma companies pursuing similar genetic strategies also poses an ongoing challenge.
The outlook for Maze is cautiously optimistic. Financially, it enters the next few years with a strengthened balance sheet and the ability to fund its key programs without immediate pressure for additional capital. Scientifically, the upcoming clinical readouts for its kidney and metabolic programs, along with progress on partnered assets, will be crucial in determining whether the 2024 turnaround is the start of a durable growth phase or a one-off spike. If the company can convert its genetic platform and current pipeline into repeatable clinical and commercial success, it could evolve into a more stable, innovation-led biotech with a stronger, more predictable earnings profile.
About Maze Therapeutics, Inc.
https://www.mazetx.comMaze Therapeutics, Inc., a clinical stage biopharmaceutical company, develops small molecule precision medicines for the treatment of renal, cardiovascular, related metabolic diseases, and obesity in the United States.
Income Statement
| Period | Revenue | Operating Expense | Net Income | Net Profit Margin | Earnings Per Share | EBITDA |
|---|---|---|---|---|---|---|
| Q3-2025 | $0 | $32.97M ▼ | $-30.09M ▲ | 0% | $-0.66 ▲ | $-29.52M ▲ |
| Q2-2025 | $0 | $35.83M ▲ | $-33.68M ▼ | 0% | $-0.77 ▼ | $-33.03M ▲ |
| Q1-2025 | $0 | $35.4M ▲ | $-32.79M ▼ | 0% | $-0.75 ▼ | $-34.72M ▼ |
| Q4-2024 | $0 ▼ | $29.73M ▲ | $-29.58M ▼ | 0% ▲ | $-0.11 ▼ | $-29.02M ▼ |
| Q3-2024 | $2.5M | $26.73M | $-24.75M | -990.08% | $-0.06 | $-23.44M |
What's going well?
Maze managed to cut its operating expenses and reduce its net loss this quarter. The company also earned some interest income, which helped soften the losses.
What's concerning?
Maze still has no revenue, so it's burning cash with no sales in sight. The rising share count means existing shareholders are getting diluted while the company remains unprofitable.
Balance Statement
| Period | Cash & Short-term | Total Assets | Total Liabilities | Total Equity |
|---|---|---|---|---|
| Q3-2025 | $383.94M ▲ | $422.06M ▲ | $42.62M ▲ | $379.44M ▲ |
| Q2-2025 | $264.54M ▼ | $303.52M ▼ | $41.28M ▲ | $262.24M ▼ |
| Q1-2025 | $294.37M ▲ | $332.84M ▲ | $40.77M ▼ | $292.07M ▲ |
| Q4-2024 | $196.81M ▲ | $240.54M ▲ | $43.64M ▼ | $196.9M ▲ |
| Q3-2024 | $149.61M | $192.48M | $93.11M | $99.37M |
What's financially strong about this company?
MAZE is sitting on a massive cash pile, has almost no debt, and can easily pay all its bills. The asset base is high quality and liquid, with no risky goodwill or intangibles. Equity is strong and growing.
What are the financial risks or weaknesses?
The company has a history of losses, as shown by large negative retained earnings. There is little sign of customer prepayments or deferred revenue, and the business may not be generating profits yet.
Cash Flow Statement
| Period | Net Income | Cash From Operations | Cash From Investing | Cash From Financing | Net Change | Free Cash Flow |
|---|---|---|---|---|---|---|
| Q3-2025 | $-30.09M ▲ | $-24.64M ▲ | $-66.88M ▼ | $143.76M ▲ | $52.23M ▲ | $-24.71M ▲ |
| Q2-2025 | $-33.68M ▼ | $-30.05M ▼ | $-393K ▼ | $612K ▼ | $-29.83M ▼ | $-30.45M ▼ |
| Q1-2025 | $-32.79M ▼ | $-29.52M ▼ | $-299K ▲ | $127.38M ▲ | $97.56M ▲ | $-29.82M ▼ |
| Q4-2024 | $-29.58M ▼ | $-22.45M ▲ | $-605K ▼ | $70.26M ▲ | $47.2M ▲ | $-23.06M ▲ |
| Q3-2024 | $-24.75M | $-23.2M | $-103K | $-2.15M | $-25.46M | $-23.31M |
What's strong about this company's cash flow?
Cash burn is shrinking, and the company now has a much bigger cash cushion after raising funds. The current cash balance gives over three years of runway at the current burn rate.
What are the cash flow concerns?
The business is not generating cash from operations and is highly dependent on raising new money, mostly by issuing more shares and diluting existing owners. Most losses are real cash burn, not just accounting.
5-Year Trend Analysis
A comprehensive look at Maze Therapeutics, Inc.'s financial evolution and strategic trajectory over the past five years.
Maze has quickly evolved from a pre-revenue biotech into a company with meaningful revenue, positive earnings, and strong cash flow in its latest year. Its balance sheet is now cash-rich with low net debt, providing a substantial runway to fund research and trials. The Compass platform offers a distinctive scientific edge, and the pipeline features multiple genetically validated drug candidates, one of which has already been licensed to a global partner. Together, these elements suggest a business with growing financial flexibility and a credible scientific foundation.
Key risks center on the early and concentrated nature of the business. Profitability and cash flow have improved, but largely on the back of a single standout year tied to a major licensing deal, not yet a diversified revenue base. The company still shows a large accumulated deficit and a limited track record of sustained profitability. Clinical and regulatory setbacks in its lead programs or underperformance by partners could materially affect both its financials and strategic position. Competition from larger biopharma companies pursuing similar genetic strategies also poses an ongoing challenge.
The outlook for Maze is cautiously optimistic. Financially, it enters the next few years with a strengthened balance sheet and the ability to fund its key programs without immediate pressure for additional capital. Scientifically, the upcoming clinical readouts for its kidney and metabolic programs, along with progress on partnered assets, will be crucial in determining whether the 2024 turnaround is the start of a durable growth phase or a one-off spike. If the company can convert its genetic platform and current pipeline into repeatable clinical and commercial success, it could evolve into a more stable, innovation-led biotech with a stronger, more predictable earnings profile.

CEO
Jason V. Coloma
Compensation Summary
(Year )
Upcoming Earnings
ETFs Holding This Stock
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Ratings Snapshot
Rating : C
Most Recent Analyst Grades
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Price Target
Institutional Ownership
TRV GP IV, LLC
Shares:6.07M
Value:$276.91M
FRAZIER LIFE SCIENCES MANAGEMENT, L.P.
Shares:4.57M
Value:$208.22M
DEEP TRACK CAPITAL, LP
Shares:4.25M
Value:$193.6M
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