PLRX - Pliant Therapeutics... Stock Analysis | Stock Taper
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Pliant Therapeutics, Inc.

PLRX

Pliant Therapeutics, Inc. NASDAQ
$1.33 2.31% (+0.03)

Market Cap $82.35 M
52w High $1.95
52w Low $1.09
P/E -0.55
Volume 424.46K
Outstanding Shares 61.91M

Income Statement

Period Revenue Operating Expense Net Income Net Profit Margin Earnings Per Share EBITDA
Q4-2025 $0 $20.71M $-23.58M 0% $-0.38 $-28.33M
Q3-2025 $0 $28.27M $-26.3M 0% $-0.43 $-23.08M
Q2-2025 $0 $45.15M $-43.3M 0% $-0.71 $-42.04M
Q1-2025 $0 $58.94M $-56.17M 0% $-0.92 $-54.92M
Q4-2024 $0 $53.32M $-49.73M 0% $-0.82 $-48.44M

Balance Statement

Period Cash & Short-term Total Assets Total Liabilities Total Equity
Q4-2025 $190.94M $225.23M $44.02M $181.21M
Q3-2025 $241.8M $276.6M $76.29M $200.31M
Q2-2025 $262.87M $299.82M $79.74M $220.08M
Q1-2025 $305.64M $344.77M $87.61M $257.16M
Q4-2024 $355.72M $396.95M $92.87M $304.08M

Cash Flow Statement

Period Net Income Cash From Operations Cash From Investing Cash From Financing Net Change Free Cash Flow
Q4-2025 $-23.58M $-17.79M $1.77M $-32.27M $-48.29M $-17.79M
Q3-2025 $-26.3M $-21.08M $27.92M $72K $6.91M $-21.08M
Q2-2025 $-43.3M $-40.6M $35.49M $0 $-5.12M $-40.72M
Q1-2025 $-56.17M $-48.86M $69.11M $498K $20.75M $-49.13M
Q4-2024 $-49.73M $-47.66M $39.13M $102K $-8.43M $-47.87M

5-Year Trend Analysis

A comprehensive look at Pliant Therapeutics, Inc.'s financial evolution and strategic trajectory over the past five years.

+ Strengths

Key strengths include a strong liquidity position with low leverage, a focused and substantial investment in R&D, and a differentiated scientific platform in integrin biology supported by a major pharmaceutical collaboration. The company’s clean balance sheet, modest fixed asset base, and concentrated spending on development rather than overhead also provide flexibility as it refocuses on oncology.

! Risks

The primary risks are sustained operating losses, heavy cash burn without current revenue, and high dependence on a few clinical-stage assets, particularly in oncology. The recent failure of a once-flagship fibrosis program highlights clinical and regulatory uncertainty. Over time, the company will likely need additional external funding, which may be influenced by market conditions and perceptions of its pipeline risk and potential.

Outlook

The outlook is that of a high-risk, high-uncertainty clinical-stage biotech undergoing a strategic pivot. Future prospects hinge on demonstrating meaningful, durable clinical benefit with its lead oncology program, advancing other integrin-based assets, and maintaining sufficient financial runway to reach key data readouts. If clinical results are favorable and capital remains accessible, the current platform could support a more robust, diversified pipeline; if not, financial and strategic options could become more constrained.