PTIX
PTIX
Protagenic Therapeutics, Inc.Income Statement
| Period | Revenue | Operating Expense | Net Income | Net Profit Margin | Earnings Per Share | EBITDA |
|---|---|---|---|---|---|---|
| Q3-2025 | $0 | $1.1M ▼ | $-869.5K ▲ | 0% | $-0.47 ▲ | $-856.92K ▲ |
| Q2-2025 | $0 | $2.33M ▲ | $-5.06M ▼ | 0% | $-1.37 ▲ | $-4.81M ▼ |
| Q1-2025 | $0 ▲ | $1.45M ▼ | $-1.44M ▲ | 0% ▼ | $-2.75 ▼ | $-1.44M ▲ |
| Q4-2024 | $-25.14K ▼ | $1.64M ▲ | $-1.55M ▼ | 6.18K% ▲ | $-0.24 ▼ | $-1.54M ▼ |
| Q3-2024 | $0 | $652.07K | $-641K | 0% | $-0.14 | $-628K |
What's going well?
PTIX cut its losses dramatically this quarter, with net loss down by over 80%. Operating expenses and interest costs both fell sharply, showing some cost control.
What's concerning?
The company has no revenue at all for two straight quarters, so it’s not bringing in any money. Even with lower costs, PTIX is still losing money and there’s no sign of a turnaround in sales.
Balance Statement
| Period | Cash & Short-term | Total Assets | Total Liabilities | Total Equity |
|---|---|---|---|---|
| Q3-2025 | $2.72M ▼ | $2.14M ▼ | $9.7M ▼ | $-7.56M ▼ |
| Q2-2025 | $4.1M ▲ | $6.49M ▲ | $10.46M ▲ | $-3.97M ▼ |
| Q1-2025 | $872.96K ▼ | $988.65K ▼ | $1.08M ▲ | $-88.33K ▼ |
| Q4-2024 | $1.84M ▲ | $1.96M ▲ | $942.76K ▲ | $1.01M ▲ |
| Q3-2024 | $1.06M | $1.51M | $789.32K | $719.01K |
What's financially strong about this company?
The only positive is that debt was reduced by about $850,000 this quarter. There are no major hidden liabilities or lease obligations.
What are the financial risks or weaknesses?
Cash is running out, liabilities are much higher than assets, and equity is deeply negative. The company cannot cover its short-term bills and has a long history of losses.
Cash Flow Statement
| Period | Net Income | Cash From Operations | Cash From Investing | Cash From Financing | Net Change | Free Cash Flow |
|---|---|---|---|---|---|---|
| Q3-2025 | $-4.49M ▲ | $-1.49M ▼ | $943.18K | $-15.41K ▼ | $1.85M ▼ | $-1.49M ▼ |
| Q2-2025 | $-5.06M ▼ | $-1.17M ▼ | $943.18K ▲ | $4.42M ▲ | $4.08M ▲ | $-1.17M ▼ |
| Q1-2025 | $-1.44M ▲ | $-1.07M ▼ | $0 | $102.52K ▼ | $-965.51K ▼ | $-1.07M ▼ |
| Q4-2024 | $-1.55M ▼ | $-819.79K ▼ | $0 | $1.6M ▲ | $782.66K ▲ | $-819.79K ▼ |
| Q3-2024 | $-640.78K | $-185.66K | $0 | $316.96K | $131.21K | $-185.66K |
What's strong about this company's cash flow?
Non-cash items help soften the losses, and the net loss is shrinking slightly. The company isn't taking on much new debt.
What are the cash flow concerns?
Cash burn is increasing, cash reserves are running low, and the business is not generating enough from operations to cover expenses. The company will need to raise more money soon.
Q4 2023 Earnings Call Summary
Read Call Summary5-Year Trend Analysis
A comprehensive look at Protagenic Therapeutics, Inc.'s financial evolution and strategic trajectory over the past five years.
Key positives include a distinctive scientific approach to stress-related disorders via the TCAP platform, a broadened pipeline across CNS and metabolic diseases following the Phytanix combination, and a management and scientific team with targeted expertise in cannabinoid drug development. Financially, the elimination of debt and maintenance of a net cash position reduce immediate balance sheet pressure. The company has also demonstrated the ability to raise capital through equity to support its R&D agenda.
Major risks center on the lack of revenue, persistent and widening losses, and accelerating cash burn, which steadily deplete assets and equity. The company’s survival and ability to execute its clinical plans depend on continued access to external financing, which can lead to ongoing shareholder dilution and has historically been accompanied by multiple reverse splits. On the operational side, the pipeline is early and exposed to high clinical, regulatory, and competitive risk, especially in crowded and technically challenging CNS and obesity markets. Integration of the merger and alignment of strategy across the combined portfolio add another layer of execution risk.
Over the near to medium term, PTIX—transitioning into Phytanix, Inc.—is likely to remain a development-stage enterprise with no commercial revenue and continuing losses. The trajectory will be driven by clinical milestones, regulatory interactions, and the company’s ability to secure capital or strategic partnerships on reasonable terms. If key programs such as PT00114 and the lead cannabinoid and neurological assets show compelling clinical data, the narrative could shift toward value creation and deal-making. Until then, the outlook is characterized by high uncertainty, dependence on external funding, and a risk-return profile typical of early-stage biotech: substantial upside potential contingent on scientific success, balanced against meaningful financial and execution risk.
About Protagenic Therapeutics, Inc.
https://www.protagenic.comProtagenic Therapeutics, Inc., a biopharmaceutical company, engages in the discovery and development of therapeutics to treat stress-related neuropsychiatric and mood disorders. Its lead compound is PT00114, a synthetic form of teneurin carboxy-terminal associated peptide, an endogenous brain signaling peptide that can dampen overactive stress responses. The company is based in New York, New York.
Income Statement
| Period | Revenue | Operating Expense | Net Income | Net Profit Margin | Earnings Per Share | EBITDA |
|---|---|---|---|---|---|---|
| Q3-2025 | $0 | $1.1M ▼ | $-869.5K ▲ | 0% | $-0.47 ▲ | $-856.92K ▲ |
| Q2-2025 | $0 | $2.33M ▲ | $-5.06M ▼ | 0% | $-1.37 ▲ | $-4.81M ▼ |
| Q1-2025 | $0 ▲ | $1.45M ▼ | $-1.44M ▲ | 0% ▼ | $-2.75 ▼ | $-1.44M ▲ |
| Q4-2024 | $-25.14K ▼ | $1.64M ▲ | $-1.55M ▼ | 6.18K% ▲ | $-0.24 ▼ | $-1.54M ▼ |
| Q3-2024 | $0 | $652.07K | $-641K | 0% | $-0.14 | $-628K |
What's going well?
PTIX cut its losses dramatically this quarter, with net loss down by over 80%. Operating expenses and interest costs both fell sharply, showing some cost control.
What's concerning?
The company has no revenue at all for two straight quarters, so it’s not bringing in any money. Even with lower costs, PTIX is still losing money and there’s no sign of a turnaround in sales.
Balance Statement
| Period | Cash & Short-term | Total Assets | Total Liabilities | Total Equity |
|---|---|---|---|---|
| Q3-2025 | $2.72M ▼ | $2.14M ▼ | $9.7M ▼ | $-7.56M ▼ |
| Q2-2025 | $4.1M ▲ | $6.49M ▲ | $10.46M ▲ | $-3.97M ▼ |
| Q1-2025 | $872.96K ▼ | $988.65K ▼ | $1.08M ▲ | $-88.33K ▼ |
| Q4-2024 | $1.84M ▲ | $1.96M ▲ | $942.76K ▲ | $1.01M ▲ |
| Q3-2024 | $1.06M | $1.51M | $789.32K | $719.01K |
What's financially strong about this company?
The only positive is that debt was reduced by about $850,000 this quarter. There are no major hidden liabilities or lease obligations.
What are the financial risks or weaknesses?
Cash is running out, liabilities are much higher than assets, and equity is deeply negative. The company cannot cover its short-term bills and has a long history of losses.
Cash Flow Statement
| Period | Net Income | Cash From Operations | Cash From Investing | Cash From Financing | Net Change | Free Cash Flow |
|---|---|---|---|---|---|---|
| Q3-2025 | $-4.49M ▲ | $-1.49M ▼ | $943.18K | $-15.41K ▼ | $1.85M ▼ | $-1.49M ▼ |
| Q2-2025 | $-5.06M ▼ | $-1.17M ▼ | $943.18K ▲ | $4.42M ▲ | $4.08M ▲ | $-1.17M ▼ |
| Q1-2025 | $-1.44M ▲ | $-1.07M ▼ | $0 | $102.52K ▼ | $-965.51K ▼ | $-1.07M ▼ |
| Q4-2024 | $-1.55M ▼ | $-819.79K ▼ | $0 | $1.6M ▲ | $782.66K ▲ | $-819.79K ▼ |
| Q3-2024 | $-640.78K | $-185.66K | $0 | $316.96K | $131.21K | $-185.66K |
What's strong about this company's cash flow?
Non-cash items help soften the losses, and the net loss is shrinking slightly. The company isn't taking on much new debt.
What are the cash flow concerns?
Cash burn is increasing, cash reserves are running low, and the business is not generating enough from operations to cover expenses. The company will need to raise more money soon.
Q4 2023 Earnings Call Summary
Read Call Summary5-Year Trend Analysis
A comprehensive look at Protagenic Therapeutics, Inc.'s financial evolution and strategic trajectory over the past five years.
Key positives include a distinctive scientific approach to stress-related disorders via the TCAP platform, a broadened pipeline across CNS and metabolic diseases following the Phytanix combination, and a management and scientific team with targeted expertise in cannabinoid drug development. Financially, the elimination of debt and maintenance of a net cash position reduce immediate balance sheet pressure. The company has also demonstrated the ability to raise capital through equity to support its R&D agenda.
Major risks center on the lack of revenue, persistent and widening losses, and accelerating cash burn, which steadily deplete assets and equity. The company’s survival and ability to execute its clinical plans depend on continued access to external financing, which can lead to ongoing shareholder dilution and has historically been accompanied by multiple reverse splits. On the operational side, the pipeline is early and exposed to high clinical, regulatory, and competitive risk, especially in crowded and technically challenging CNS and obesity markets. Integration of the merger and alignment of strategy across the combined portfolio add another layer of execution risk.
Over the near to medium term, PTIX—transitioning into Phytanix, Inc.—is likely to remain a development-stage enterprise with no commercial revenue and continuing losses. The trajectory will be driven by clinical milestones, regulatory interactions, and the company’s ability to secure capital or strategic partnerships on reasonable terms. If key programs such as PT00114 and the lead cannabinoid and neurological assets show compelling clinical data, the narrative could shift toward value creation and deal-making. Until then, the outlook is characterized by high uncertainty, dependence on external funding, and a risk-return profile typical of early-stage biotech: substantial upside potential contingent on scientific success, balanced against meaningful financial and execution risk.

CEO
Garo H. Armen
Compensation Summary
(Year )
Upcoming Earnings
Split Record
| Date | Type | Ratio |
|---|---|---|
| 2025-05-05 | Reverse | 1:14 |
| 2023-03-23 | Reverse | 1:4 |
ETFs Holding This Stock
Summary
Showing Top 1 of 1
Ratings Snapshot
Rating : C+
Price Target
Institutional Ownership
CT FINANCIAL ADVISORS LLC
Shares:1
Value:$0.45
CONCOURSE FINANCIAL GROUP SECURITIES, INC.
Shares:0
Value:$0
Summary
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