PTIXW
PTIXW
Protagenic Therapeutics, Inc.Income Statement
| Period | Revenue | Operating Expense | Net Income | Net Profit Margin | Earnings Per Share | EBITDA |
|---|---|---|---|---|---|---|
| Q3-2025 | $0 | $1.1M ▼ | $-869.5K ▲ | 0% | $-0.47 ▲ | $-856.92K ▲ |
| Q2-2025 | $0 | $2.33M ▲ | $-5.06M ▼ | 0% | $-1.37 ▲ | $-4.81M ▼ |
| Q1-2025 | $0 ▲ | $1.45M ▼ | $-1.44M ▲ | 0% ▼ | $-2.75 ▼ | $-1.44M ▲ |
| Q4-2024 | $-25.14K ▼ | $1.64M ▲ | $-1.55M ▼ | 6.18K% ▲ | $-0.24 ▼ | $-1.54M ▼ |
| Q3-2024 | $0 | $652.07K | $-641K | 0% | $-0.14 | $-628K |
What's going well?
The company has cut its losses dramatically, with net loss down by over $4 million from last quarter. Operating expenses and interest costs are both much lower, suggesting management is tightening spending.
What's concerning?
There is still no revenue at all, so the business is burning cash with no sign of sales. The company remains deeply unprofitable, and it's unclear how long it can keep operating without income.
Balance Statement
| Period | Cash & Short-term | Total Assets | Total Liabilities | Total Equity |
|---|---|---|---|---|
| Q3-2025 | $2.72M ▼ | $2.14M ▼ | $9.7M ▼ | $-7.56M ▼ |
| Q2-2025 | $4.1M ▲ | $6.49M ▲ | $10.46M ▲ | $-3.97M ▼ |
| Q1-2025 | $872.96K ▼ | $988.65K ▼ | $1.08M ▲ | $-88.33K ▼ |
| Q4-2024 | $1.84M ▲ | $1.96M ▲ | $942.76K ▲ | $1.01M ▲ |
| Q3-2024 | $1.06M | $1.51M | $789.32K | $719.01K |
What's financially strong about this company?
They managed to pay down some debt this quarter, and have a small cash cushion left. There are no large hidden or off-balance-sheet liabilities.
What are the financial risks or weaknesses?
The company owes far more than it owns, has negative equity, and its cash is running out fast. All debt is due soon, and assets are mostly intangible, making survival without new funding unlikely.
Cash Flow Statement
| Period | Net Income | Cash From Operations | Cash From Investing | Cash From Financing | Net Change | Free Cash Flow |
|---|---|---|---|---|---|---|
| Q3-2025 | $-4.49M ▲ | $-1.49M ▼ | $943.18K | $-15.41K ▼ | $1.85M ▼ | $-1.49M ▼ |
| Q2-2025 | $-5.06M ▼ | $-1.17M ▼ | $943.18K ▲ | $4.42M ▲ | $4.08M ▲ | $-1.17M ▼ |
| Q1-2025 | $-1.44M ▲ | $-1.07M ▼ | $0 | $102.52K ▼ | $-965.51K ▼ | $-1.07M ▼ |
| Q4-2024 | $-1.55M ▼ | $-819.79K ▼ | $0 | $1.6M ▲ | $782.66K ▲ | $-819.79K ▼ |
| Q3-2024 | $-640.78K | $-185.66K | $0 | $316.96K | $131.21K | $-185.66K |
What's strong about this company's cash flow?
Non-cash charges make up much of the losses, so actual cash burn is less than the headline net loss. The company is not taking on new debt or diluting shareholders this quarter.
What are the cash flow concerns?
Operating cash burn is rising, cash is running low, and the company is dependent on outside funding to survive. No meaningful investment in growth or shareholder returns.
Q4 2023 Earnings Call Summary
Read Call Summary5-Year Trend Analysis
A comprehensive look at Protagenic Therapeutics, Inc.'s financial evolution and strategic trajectory over the past five years.
Key positives include a differentiated scientific approach in CNS disorders, a diversified pipeline spanning peptides, cannabinoid‑like compounds, and other novel mechanisms, and leadership experience tied to prior successes in cannabis‑derived medicines. The company has eliminated financial debt and operates with net cash, which reduces balance‑sheet risk. Management has shown a willingness to invest in R&D and to restructure the organization to focus on the most promising assets, suggesting strategic flexibility.
Major concerns center on financial sustainability and development risk. The company has no revenue, persistent and growing losses, shrinking cash and equity, and relies heavily on external equity financing, which can be dilutive and uncertain. Clinical, regulatory, and commercial risks are high in CNS indications, and competition from larger, better‑funded players is intense. The shrinking liquidity buffer increases the sensitivity of the story to trial timing and financing windows, leaving little room for setbacks.
The forward picture is highly binary and dependent on execution. In the near term, investors and stakeholders are likely to focus on three questions: whether the company can generate compelling mid‑stage data for PT00114, whether it can advance key Phytanix‑derived assets (especially in obesity and other high‑value indications) into the clinic, and whether it can secure sufficient funding or partnerships to support these efforts without overwhelming dilution. If clinical results are strong and capital is available, the scientific platform could unlock meaningful value; if trials disappoint or funding tightens, the current rate of cash burn and balance‑sheet contraction pose clear challenges to the long‑term outlook.
About Protagenic Therapeutics, Inc.
http://www.protagenic.comProtagenic Therapeutics, Inc., a pre-clinical biopharmaceutical company, engages in the discovery and development of therapeutics to treat stress-related neuropsychiatric and mood disorders. Its lead compound, PT00114 is a synthetic form of teneurin carboxy-terminal associated peptide, an endogenous brain signaling peptide that can dampen overactive stress responses.
Income Statement
| Period | Revenue | Operating Expense | Net Income | Net Profit Margin | Earnings Per Share | EBITDA |
|---|---|---|---|---|---|---|
| Q3-2025 | $0 | $1.1M ▼ | $-869.5K ▲ | 0% | $-0.47 ▲ | $-856.92K ▲ |
| Q2-2025 | $0 | $2.33M ▲ | $-5.06M ▼ | 0% | $-1.37 ▲ | $-4.81M ▼ |
| Q1-2025 | $0 ▲ | $1.45M ▼ | $-1.44M ▲ | 0% ▼ | $-2.75 ▼ | $-1.44M ▲ |
| Q4-2024 | $-25.14K ▼ | $1.64M ▲ | $-1.55M ▼ | 6.18K% ▲ | $-0.24 ▼ | $-1.54M ▼ |
| Q3-2024 | $0 | $652.07K | $-641K | 0% | $-0.14 | $-628K |
What's going well?
The company has cut its losses dramatically, with net loss down by over $4 million from last quarter. Operating expenses and interest costs are both much lower, suggesting management is tightening spending.
What's concerning?
There is still no revenue at all, so the business is burning cash with no sign of sales. The company remains deeply unprofitable, and it's unclear how long it can keep operating without income.
Balance Statement
| Period | Cash & Short-term | Total Assets | Total Liabilities | Total Equity |
|---|---|---|---|---|
| Q3-2025 | $2.72M ▼ | $2.14M ▼ | $9.7M ▼ | $-7.56M ▼ |
| Q2-2025 | $4.1M ▲ | $6.49M ▲ | $10.46M ▲ | $-3.97M ▼ |
| Q1-2025 | $872.96K ▼ | $988.65K ▼ | $1.08M ▲ | $-88.33K ▼ |
| Q4-2024 | $1.84M ▲ | $1.96M ▲ | $942.76K ▲ | $1.01M ▲ |
| Q3-2024 | $1.06M | $1.51M | $789.32K | $719.01K |
What's financially strong about this company?
They managed to pay down some debt this quarter, and have a small cash cushion left. There are no large hidden or off-balance-sheet liabilities.
What are the financial risks or weaknesses?
The company owes far more than it owns, has negative equity, and its cash is running out fast. All debt is due soon, and assets are mostly intangible, making survival without new funding unlikely.
Cash Flow Statement
| Period | Net Income | Cash From Operations | Cash From Investing | Cash From Financing | Net Change | Free Cash Flow |
|---|---|---|---|---|---|---|
| Q3-2025 | $-4.49M ▲ | $-1.49M ▼ | $943.18K | $-15.41K ▼ | $1.85M ▼ | $-1.49M ▼ |
| Q2-2025 | $-5.06M ▼ | $-1.17M ▼ | $943.18K ▲ | $4.42M ▲ | $4.08M ▲ | $-1.17M ▼ |
| Q1-2025 | $-1.44M ▲ | $-1.07M ▼ | $0 | $102.52K ▼ | $-965.51K ▼ | $-1.07M ▼ |
| Q4-2024 | $-1.55M ▼ | $-819.79K ▼ | $0 | $1.6M ▲ | $782.66K ▲ | $-819.79K ▼ |
| Q3-2024 | $-640.78K | $-185.66K | $0 | $316.96K | $131.21K | $-185.66K |
What's strong about this company's cash flow?
Non-cash charges make up much of the losses, so actual cash burn is less than the headline net loss. The company is not taking on new debt or diluting shareholders this quarter.
What are the cash flow concerns?
Operating cash burn is rising, cash is running low, and the company is dependent on outside funding to survive. No meaningful investment in growth or shareholder returns.
Q4 2023 Earnings Call Summary
Read Call Summary5-Year Trend Analysis
A comprehensive look at Protagenic Therapeutics, Inc.'s financial evolution and strategic trajectory over the past five years.
Key positives include a differentiated scientific approach in CNS disorders, a diversified pipeline spanning peptides, cannabinoid‑like compounds, and other novel mechanisms, and leadership experience tied to prior successes in cannabis‑derived medicines. The company has eliminated financial debt and operates with net cash, which reduces balance‑sheet risk. Management has shown a willingness to invest in R&D and to restructure the organization to focus on the most promising assets, suggesting strategic flexibility.
Major concerns center on financial sustainability and development risk. The company has no revenue, persistent and growing losses, shrinking cash and equity, and relies heavily on external equity financing, which can be dilutive and uncertain. Clinical, regulatory, and commercial risks are high in CNS indications, and competition from larger, better‑funded players is intense. The shrinking liquidity buffer increases the sensitivity of the story to trial timing and financing windows, leaving little room for setbacks.
The forward picture is highly binary and dependent on execution. In the near term, investors and stakeholders are likely to focus on three questions: whether the company can generate compelling mid‑stage data for PT00114, whether it can advance key Phytanix‑derived assets (especially in obesity and other high‑value indications) into the clinic, and whether it can secure sufficient funding or partnerships to support these efforts without overwhelming dilution. If clinical results are strong and capital is available, the scientific platform could unlock meaningful value; if trials disappoint or funding tightens, the current rate of cash burn and balance‑sheet contraction pose clear challenges to the long‑term outlook.

CEO
Garo H. Armen
Compensation Summary
(Year 2008)
Price Target
Institutional Ownership
CLEAR STREET GROUP INC.
Shares:100K
Value:$1.5K
CLEAR STREET LLC
Shares:100K
Value:$1.5K
SUSQUEHANNA INTERNATIONAL GROUP, LLP
Shares:87.6K
Value:$1.31K
Summary
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