SHPH
SHPH
Shuttle Pharmaceuticals Holdings, Inc.Income Statement
| Period | Revenue | Operating Expense | Net Income | Net Profit Margin | Earnings Per Share | EBITDA |
|---|---|---|---|---|---|---|
| Q3-2025 | $0 | $2.27M ▼ | $-2.35M ▲ | 0% | $-1.05 ▲ | $-2.33M ▲ |
| Q2-2025 | $0 | $3.91M ▲ | $-3.71M ▼ | 0% | $-3.29 ▼ | $-3.91M ▼ |
| Q1-2025 | $0 | $2.95M ▲ | $-3.05M ▼ | 0% | $-0.75 ▼ | $-3.04M ▼ |
| Q4-2024 | $0 | $1.78M ▼ | $-1.6M ▲ | 0% | $-0.54 ▼ | $-1.44M ▲ |
| Q3-2024 | $0 | $3.05M | $-3.78M | 0% | $-0.37 | $-3.51M |
What's going well?
The company managed to cut its operating expenses significantly, reducing its net loss by over $1 million. Per-share losses also narrowed as a result.
What's concerning?
There is still no revenue, so the business is not generating any sales. Heavy spending continues, and share dilution means existing shareholders now own less of the company.
Balance Statement
| Period | Cash & Short-term | Total Assets | Total Liabilities | Total Equity |
|---|---|---|---|---|
| Q3-2025 | $2.09M ▼ | $3.54M ▼ | $2.15M ▲ | $1.39M ▼ |
| Q2-2025 | $4.82M ▲ | $5.5M ▲ | $1.9M ▼ | $3.61M ▲ |
| Q1-2025 | $4.51M ▲ | $5.31M ▲ | $2.02M ▲ | $3.29M ▲ |
| Q4-2024 | $1.92M ▲ | $2.51M ▲ | $1.8M ▼ | $709.15K ▲ |
| Q3-2024 | $156.66K | $673.57K | $1.99M | $-1.32M |
What's financially strong about this company?
The company has no goodwill or intangible assets, so its assets are high quality and mostly cash. Debt is low and manageable, and there are no hidden liabilities.
What are the financial risks or weaknesses?
Cash and equity have both fallen sharply in just one quarter, and the company has a long history of losses. If this trend continues, they could run into trouble soon.
Cash Flow Statement
| Period | Net Income | Cash From Operations | Cash From Investing | Cash From Financing | Net Change | Free Cash Flow |
|---|---|---|---|---|---|---|
| Q3-2025 | $-2.35M ▲ | $-2.63M ▲ | $0 | $-96.38K ▼ | $-2.72M ▼ | $-2.63M ▲ |
| Q2-2025 | $-3.71M ▼ | $-3.36M ▼ | $0 | $3.66M ▼ | $305.06K ▼ | $-3.36M ▼ |
| Q1-2025 | $-3.05M ▼ | $-2.53M ▲ | $0 | $5.12M ▲ | $2.59M ▲ | $-2.53M ▲ |
| Q4-2024 | $-1.6M ▲ | $-2.69M ▼ | $0 ▼ | $4.45M ▲ | $1.76M ▲ | $-2.69M ▼ |
| Q3-2024 | $-3.78M | $-2M | $1.66M | $-196.79K | $-538.94K | $-2M |
What's strong about this company's cash flow?
Cash burn is shrinking quarter over quarter, and the company is no longer diluting shareholders with new stock. Capital spending is very low, so there's no big drain from investments.
What are the cash flow concerns?
The company is still burning over $2.6 million in cash each quarter, with only $2.1 million left—runway is tight. No profits, no dividends, and working capital is now draining cash.
5-Year Trend Analysis
A comprehensive look at Shuttle Pharmaceuticals Holdings, Inc.'s financial evolution and strategic trajectory over the past five years.
Key positives include a clear scientific focus on making radiation therapy more effective, a lead asset already in mid‑stage trials with orphan designation, and a complementary pipeline of HDAC inhibitors and diagnostics. The partnership with an academic medical center and the acquisition of an AI‑driven discovery platform add both credibility and potential speed to development. Historically, the company has shown an ability to raise capital to fund its R&D ambitions, and its balance sheet, while weakened, has at times been strong enough to support aggressive research investment.
Major risks stem from the combination of clinical uncertainty and financial fragility. The company has no revenue and escalating losses, with cash burn increasing significantly over time. Liquidity has tightened as cash reserves have fallen and equity has been eroded, making continued access to capital markets critical. A setback in the lead clinical program or delays in the pipeline would intensify funding pressure. Competition from larger oncology players, the complexity of proving added benefit over existing radiation and drug regimens, and general biotech market volatility all add further layers of risk.
The outlook is highly binary and hinges on clinical and financing milestones. If the lead radiosensitizer generates strong Phase 2 and later‑stage data and the AI‑enhanced pipeline begins to produce credible follow‑on candidates, the company’s scientific strategy could gain substantial validation and open a path toward eventual commercialization. Conversely, continued cash burn without clear clinical wins or an inability to secure additional funding would constrain operations and could force strategic shifts or scaling back of programs. In short, the future trajectory depends far more on trial results and capital access than on any current financial performance, which remains firmly in investment mode.
About Shuttle Pharmaceuticals Holdings, Inc.
https://www.shuttlepharma.comShuttle Pharmaceuticals Holdings, Inc., through its subsidiary, Shuttle Pharmaceuticals, Inc., focuses on the discovery, development, and commercialization of drugs for sensitizing cancers to radiation therapy.
Income Statement
| Period | Revenue | Operating Expense | Net Income | Net Profit Margin | Earnings Per Share | EBITDA |
|---|---|---|---|---|---|---|
| Q3-2025 | $0 | $2.27M ▼ | $-2.35M ▲ | 0% | $-1.05 ▲ | $-2.33M ▲ |
| Q2-2025 | $0 | $3.91M ▲ | $-3.71M ▼ | 0% | $-3.29 ▼ | $-3.91M ▼ |
| Q1-2025 | $0 | $2.95M ▲ | $-3.05M ▼ | 0% | $-0.75 ▼ | $-3.04M ▼ |
| Q4-2024 | $0 | $1.78M ▼ | $-1.6M ▲ | 0% | $-0.54 ▼ | $-1.44M ▲ |
| Q3-2024 | $0 | $3.05M | $-3.78M | 0% | $-0.37 | $-3.51M |
What's going well?
The company managed to cut its operating expenses significantly, reducing its net loss by over $1 million. Per-share losses also narrowed as a result.
What's concerning?
There is still no revenue, so the business is not generating any sales. Heavy spending continues, and share dilution means existing shareholders now own less of the company.
Balance Statement
| Period | Cash & Short-term | Total Assets | Total Liabilities | Total Equity |
|---|---|---|---|---|
| Q3-2025 | $2.09M ▼ | $3.54M ▼ | $2.15M ▲ | $1.39M ▼ |
| Q2-2025 | $4.82M ▲ | $5.5M ▲ | $1.9M ▼ | $3.61M ▲ |
| Q1-2025 | $4.51M ▲ | $5.31M ▲ | $2.02M ▲ | $3.29M ▲ |
| Q4-2024 | $1.92M ▲ | $2.51M ▲ | $1.8M ▼ | $709.15K ▲ |
| Q3-2024 | $156.66K | $673.57K | $1.99M | $-1.32M |
What's financially strong about this company?
The company has no goodwill or intangible assets, so its assets are high quality and mostly cash. Debt is low and manageable, and there are no hidden liabilities.
What are the financial risks or weaknesses?
Cash and equity have both fallen sharply in just one quarter, and the company has a long history of losses. If this trend continues, they could run into trouble soon.
Cash Flow Statement
| Period | Net Income | Cash From Operations | Cash From Investing | Cash From Financing | Net Change | Free Cash Flow |
|---|---|---|---|---|---|---|
| Q3-2025 | $-2.35M ▲ | $-2.63M ▲ | $0 | $-96.38K ▼ | $-2.72M ▼ | $-2.63M ▲ |
| Q2-2025 | $-3.71M ▼ | $-3.36M ▼ | $0 | $3.66M ▼ | $305.06K ▼ | $-3.36M ▼ |
| Q1-2025 | $-3.05M ▼ | $-2.53M ▲ | $0 | $5.12M ▲ | $2.59M ▲ | $-2.53M ▲ |
| Q4-2024 | $-1.6M ▲ | $-2.69M ▼ | $0 ▼ | $4.45M ▲ | $1.76M ▲ | $-2.69M ▼ |
| Q3-2024 | $-3.78M | $-2M | $1.66M | $-196.79K | $-538.94K | $-2M |
What's strong about this company's cash flow?
Cash burn is shrinking quarter over quarter, and the company is no longer diluting shareholders with new stock. Capital spending is very low, so there's no big drain from investments.
What are the cash flow concerns?
The company is still burning over $2.6 million in cash each quarter, with only $2.1 million left—runway is tight. No profits, no dividends, and working capital is now draining cash.
5-Year Trend Analysis
A comprehensive look at Shuttle Pharmaceuticals Holdings, Inc.'s financial evolution and strategic trajectory over the past five years.
Key positives include a clear scientific focus on making radiation therapy more effective, a lead asset already in mid‑stage trials with orphan designation, and a complementary pipeline of HDAC inhibitors and diagnostics. The partnership with an academic medical center and the acquisition of an AI‑driven discovery platform add both credibility and potential speed to development. Historically, the company has shown an ability to raise capital to fund its R&D ambitions, and its balance sheet, while weakened, has at times been strong enough to support aggressive research investment.
Major risks stem from the combination of clinical uncertainty and financial fragility. The company has no revenue and escalating losses, with cash burn increasing significantly over time. Liquidity has tightened as cash reserves have fallen and equity has been eroded, making continued access to capital markets critical. A setback in the lead clinical program or delays in the pipeline would intensify funding pressure. Competition from larger oncology players, the complexity of proving added benefit over existing radiation and drug regimens, and general biotech market volatility all add further layers of risk.
The outlook is highly binary and hinges on clinical and financing milestones. If the lead radiosensitizer generates strong Phase 2 and later‑stage data and the AI‑enhanced pipeline begins to produce credible follow‑on candidates, the company’s scientific strategy could gain substantial validation and open a path toward eventual commercialization. Conversely, continued cash burn without clear clinical wins or an inability to secure additional funding would constrain operations and could force strategic shifts or scaling back of programs. In short, the future trajectory depends far more on trial results and capital access than on any current financial performance, which remains firmly in investment mode.

CEO
Christopher Robert Cooper BBA, MBA
Compensation Summary
(Year 2024)
Split Record
| Date | Type | Ratio |
|---|---|---|
| 2025-06-16 | Reverse | 1:25 |
| 2024-08-13 | Reverse | 1:8 |
Ratings Snapshot
Rating : C
Price Target
Institutional Ownership
Summary
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