SLN - Silence Therapeutics... Stock Analysis | Stock Taper
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Silence Therapeutics plc

SLN

Silence Therapeutics plc NASDAQ
$7.46 2.47% (+0.18)

Market Cap $343.86 M
52w High $7.91
52w Low $2.88
P/E -3.95
Volume 618.70K
Outstanding Shares 47.23M

Income Statement

Period Revenue Operating Expense Net Income Net Profit Margin Earnings Per Share EBITDA
Q4-2025 $34K $12.48M $-11.77M -34.62K% $-0.27 $-12.35M
Q3-2025 $159K $26.34M $-20.96M -13.18K% $-1.32 $-20.8M
Q2-2025 $224K $24.1M $-27.35M -12.21K% $-1.74 $-22.49M
Q1-2025 $142K $28.5M $-28.53M -20.09K% $-1.8 $-28.27M
Q4-2024 $24.33M $25.8M $14.17M 58.26% $0.9 $7.19M

Balance Statement

Period Cash & Short-term Total Assets Total Liabilities Total Equity
Q4-2025 $85.11M $131.44M $69.14M $62.3M
Q3-2025 $102.19M $146.79M $72.73M $74.06M
Q2-2025 $114.16M $165.23M $71.08M $94.16M
Q1-2025 $136.53M $185.3M $298.04M $-112.74M
Q4-2024 $147.33M $202.63M $68.61M $134.02M

Cash Flow Statement

Period Net Income Cash From Operations Cash From Investing Cash From Financing Net Change Free Cash Flow
Q4-2025 $-82.17M $-17.29M $-53.34M $-14.09 $-70.75M $-17.34M
Q3-2025 $-20.96M $-10.89M $51.29M $0 $40.29M $-10.89M
Q2-2025 $-27.35M $-21.78M $-1.56M $1K $-23.15M $-21.83M
Q1-2025 $-22.08M $-12.31M $-44.38M $14K $-56.44M $-12.31M
Q4-2024 $22.89M $-22.06M $49.78M $1.12M $59.38M $-24.92M

Revenue by Products

Product Q1-2025Q2-2025Q4-2025
Research Collaboration Income
Research Collaboration Income
$0 $0 $0

Q4 2024 Earnings Call Summary

Read Call Summary

5-Year Trend Analysis

A comprehensive look at Silence Therapeutics plc's financial evolution and strategic trajectory over the past five years.

+ Strengths

Key strengths include a differentiated RNAi platform with clinically validated potential, a pipeline that spans both large cardiovascular markets and rare diseases, and strategic partnerships with major pharma that provide validation and potential non‑dilutive funding. The balance sheet currently shows meaningful cash and minimal debt, allowing management to focus on science. A long history in RNAi and a robust intellectual property portfolio further reinforce its technical foundation.

! Risks

The main risks are substantial and typical for development‑stage biotech: persistent heavy losses, large negative cash flow, and reliance on future financings or partnership deals to stay funded. Scientific and regulatory uncertainty is high, particularly around pivotal trials for its lead programs. Competitive pressure from larger RNAi players and alternative genetic technologies could erode its opportunity. Additionally, anomalies in the reported balance sheet figures introduce some uncertainty around the precise financial picture and warrant careful scrutiny.

Outlook

The outlook for SLN is highly dependent on a few key events: successful partnering of its lead cardiovascular program, positive mid‑ and late‑stage clinical data, and continued access to capital. If these elements align, the company could transition from a purely R&D story toward a more mature, royalty‑ and product‑driven model over time. If clinical or funding setbacks occur, the current cash burn and small revenue base leave limited room for error. Overall, SLN represents a classic high‑risk, innovation‑driven biotech profile where outcomes hinge on scientific execution and deal‑making rather than near‑term financial metrics.