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GeneDx Holdings Corp.Income Statement
| Period | Revenue | Operating Expense | Net Income | Net Profit Margin | Earnings Per Share | EBITDA |
|---|---|---|---|---|---|---|
| Q4-2025 | $120.99M ▲ | $92.64M ▲ | $-17.67M ▼ | -14.6% ▼ | $-0.61 ▼ | $-10.83M ▼ |
| Q3-2025 | $116.74M ▲ | $87.78M ▲ | $-7.63M ▼ | -6.54% ▼ | $-0.27 ▼ | $-352K ▼ |
| Q2-2025 | $102.69M ▲ | $61.94M ▼ | $10.81M ▲ | 10.53% ▲ | $0.38 ▲ | $17.57M ▲ |
| Q1-2025 | $87.11M ▼ | $63.03M ▲ | $-6.53M ▼ | -7.49% ▼ | $-0.23 ▼ | $236K ▼ |
| Q4-2024 | $95.64M | $57.4M | $5.44M | 5.69% | $0.2 | $14.36M |
Balance Statement
| Period | Cash & Short-term | Total Assets | Total Liabilities | Total Equity |
|---|---|---|---|---|
| Q4-2025 | $171.28M ▲ | $570.19M ▲ | $262.01M ▲ | $308.18M ▲ |
| Q3-2025 | $155.08M ▲ | $493.9M ▲ | $201.64M ▲ | $292.26M ▲ |
| Q2-2025 | $134.56M ▼ | $463.86M ▲ | $186.73M ▼ | $277.13M ▲ |
| Q1-2025 | $159.16M ▲ | $446.43M ▲ | $189.03M ▲ | $257.4M ▲ |
| Q4-2024 | $141.19M | $419.38M | $174.13M | $245.25M |
Cash Flow Statement
| Period | Net Income | Cash From Operations | Cash From Investing | Cash From Financing | Net Change | Free Cash Flow |
|---|---|---|---|---|---|---|
| Q4-2025 | $-17.67M ▼ | $-3.09M ▼ | $-11.07M ▼ | $23.19M ▲ | $9.03M ▼ | $-7.44M ▼ |
| Q3-2025 | $-7.63M ▼ | $15.77M ▲ | $-4.69M ▲ | $10.77M ▲ | $21.85M ▲ | $9.6M ▲ |
| Q2-2025 | $10.81M ▲ | $10.42M ▲ | $-36.35M ▼ | $346K ▼ | $-25.58M ▼ | $8.05M ▲ |
| Q1-2025 | $-6.53M ▼ | $10.18M ▲ | $-9.41M ▼ | $13.72M ▼ | $14.49M ▼ | $4.05M ▲ |
| Q4-2024 | $5.44M | $-3.18M | $-519K | $31.02M | $27.32M | $-6.23M |
Revenue by Products
| Product | Q1-2025 | Q2-2025 | Q3-2025 | Q4-2025 |
|---|---|---|---|---|
Diagnostic Test | $90.00M ▲ | $100.00M ▲ | $110.00M ▲ | $120.00M ▲ |
Diagnostic Test Institutional Customers | $20.00M ▲ | $20.00M ▲ | $20.00M ▲ | $20.00M ▲ |
Diagnostic Test Self Pay | $0 ▲ | $0 ▲ | $0 ▲ | $0 ▲ |
Diagnostic Test Third Party Insurance | $70.00M ▲ | $80.00M ▲ | $100.00M ▲ | $100.00M ▲ |
Product and Service Other | $0 ▲ | $0 ▲ | $0 ▲ | $0 ▲ |
Q4 2025 Earnings Call Summary
Read Call Summary5-Year Trend Analysis
A comprehensive look at GeneDx Holdings Corp.'s financial evolution and strategic trajectory over the past five years.
Key strengths include a strong position in rare disease genomics, a unique and highly valuable dataset, advanced AI and bioinformatics capabilities, and a product suite recognized for clinical innovation and speed. Financially, the company benefits from robust gross margins, positive operating and free cash flow in the latest period, and a balance sheet characterized by solid liquidity and low net leverage. The growth pipeline is broad, spanning prenatal, pediatric, critical care, and international markets, with opportunities in both diagnostics and software.
Major risks center on sustained unprofitability at the operating and net income levels, substantial accumulated losses, and a cost structure that is currently heavy relative to revenue. The business relies heavily on intangible assets, acquisitions, and ongoing R&D spending, all of which increase execution and valuation risk. Competitive intensity, reimbursement uncertainty, regulatory oversight, and the need to successfully transition toward a more software- and platform-based model add further complexity. Limited historical financial data also makes it harder to assess the durability of recent cash-generation patterns.
Looking ahead, GeneDx appears positioned as a high-potential but still maturing healthcare technology company. Its data and technology assets could support meaningful growth and eventual margin expansion if management can scale revenues faster than costs and maintain its innovation edge. The strong liquidity and net cash position provide time and flexibility to pursue this strategy, but the path to consistent profitability and stable cash flows remains uncertain and will depend on successful execution across multiple fronts—commercial, technological, regulatory, and operational.
About GeneDx Holdings Corp.
https://www.genedx.comGeneDx Holdings Corp., through its subsidiaries, provides genomics-related diagnostic and information services. The company offers Centrellis, an AI-driven health intelligence platform that integrates digital tools and artificial intelligence allowing scientists to ingest and synthesize clinical and genomic data to deliver comprehensive health insights.
Income Statement
| Period | Revenue | Operating Expense | Net Income | Net Profit Margin | Earnings Per Share | EBITDA |
|---|---|---|---|---|---|---|
| Q4-2025 | $120.99M ▲ | $92.64M ▲ | $-17.67M ▼ | -14.6% ▼ | $-0.61 ▼ | $-10.83M ▼ |
| Q3-2025 | $116.74M ▲ | $87.78M ▲ | $-7.63M ▼ | -6.54% ▼ | $-0.27 ▼ | $-352K ▼ |
| Q2-2025 | $102.69M ▲ | $61.94M ▼ | $10.81M ▲ | 10.53% ▲ | $0.38 ▲ | $17.57M ▲ |
| Q1-2025 | $87.11M ▼ | $63.03M ▲ | $-6.53M ▼ | -7.49% ▼ | $-0.23 ▼ | $236K ▼ |
| Q4-2024 | $95.64M | $57.4M | $5.44M | 5.69% | $0.2 | $14.36M |
Balance Statement
| Period | Cash & Short-term | Total Assets | Total Liabilities | Total Equity |
|---|---|---|---|---|
| Q4-2025 | $171.28M ▲ | $570.19M ▲ | $262.01M ▲ | $308.18M ▲ |
| Q3-2025 | $155.08M ▲ | $493.9M ▲ | $201.64M ▲ | $292.26M ▲ |
| Q2-2025 | $134.56M ▼ | $463.86M ▲ | $186.73M ▼ | $277.13M ▲ |
| Q1-2025 | $159.16M ▲ | $446.43M ▲ | $189.03M ▲ | $257.4M ▲ |
| Q4-2024 | $141.19M | $419.38M | $174.13M | $245.25M |
Cash Flow Statement
| Period | Net Income | Cash From Operations | Cash From Investing | Cash From Financing | Net Change | Free Cash Flow |
|---|---|---|---|---|---|---|
| Q4-2025 | $-17.67M ▼ | $-3.09M ▼ | $-11.07M ▼ | $23.19M ▲ | $9.03M ▼ | $-7.44M ▼ |
| Q3-2025 | $-7.63M ▼ | $15.77M ▲ | $-4.69M ▲ | $10.77M ▲ | $21.85M ▲ | $9.6M ▲ |
| Q2-2025 | $10.81M ▲ | $10.42M ▲ | $-36.35M ▼ | $346K ▼ | $-25.58M ▼ | $8.05M ▲ |
| Q1-2025 | $-6.53M ▼ | $10.18M ▲ | $-9.41M ▼ | $13.72M ▼ | $14.49M ▼ | $4.05M ▲ |
| Q4-2024 | $5.44M | $-3.18M | $-519K | $31.02M | $27.32M | $-6.23M |
Revenue by Products
| Product | Q1-2025 | Q2-2025 | Q3-2025 | Q4-2025 |
|---|---|---|---|---|
Diagnostic Test | $90.00M ▲ | $100.00M ▲ | $110.00M ▲ | $120.00M ▲ |
Diagnostic Test Institutional Customers | $20.00M ▲ | $20.00M ▲ | $20.00M ▲ | $20.00M ▲ |
Diagnostic Test Self Pay | $0 ▲ | $0 ▲ | $0 ▲ | $0 ▲ |
Diagnostic Test Third Party Insurance | $70.00M ▲ | $80.00M ▲ | $100.00M ▲ | $100.00M ▲ |
Product and Service Other | $0 ▲ | $0 ▲ | $0 ▲ | $0 ▲ |
Q4 2025 Earnings Call Summary
Read Call Summary5-Year Trend Analysis
A comprehensive look at GeneDx Holdings Corp.'s financial evolution and strategic trajectory over the past five years.
Key strengths include a strong position in rare disease genomics, a unique and highly valuable dataset, advanced AI and bioinformatics capabilities, and a product suite recognized for clinical innovation and speed. Financially, the company benefits from robust gross margins, positive operating and free cash flow in the latest period, and a balance sheet characterized by solid liquidity and low net leverage. The growth pipeline is broad, spanning prenatal, pediatric, critical care, and international markets, with opportunities in both diagnostics and software.
Major risks center on sustained unprofitability at the operating and net income levels, substantial accumulated losses, and a cost structure that is currently heavy relative to revenue. The business relies heavily on intangible assets, acquisitions, and ongoing R&D spending, all of which increase execution and valuation risk. Competitive intensity, reimbursement uncertainty, regulatory oversight, and the need to successfully transition toward a more software- and platform-based model add further complexity. Limited historical financial data also makes it harder to assess the durability of recent cash-generation patterns.
Looking ahead, GeneDx appears positioned as a high-potential but still maturing healthcare technology company. Its data and technology assets could support meaningful growth and eventual margin expansion if management can scale revenues faster than costs and maintain its innovation edge. The strong liquidity and net cash position provide time and flexibility to pursue this strategy, but the path to consistent profitability and stable cash flows remains uncertain and will depend on successful execution across multiple fronts—commercial, technological, regulatory, and operational.

CEO
Katherine A. Stueland
Compensation Summary
(Year )
Ratings Snapshot
Rating : C+
Price Target
Institutional Ownership
LMR PARTNERS LLP
Shares:2.14M
Value:$18.58K
COWEN AND COMPANY, LLC
Shares:800.66K
Value:$6.97K
D. E. SHAW & CO., INC.
Shares:467.2K
Value:$4.06K
Summary
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