WVE
WVE
Wave Life Sciences Ltd.Income Statement
| Period | Revenue | Operating Expense | Net Income | Net Profit Margin | Earnings Per Share | EBITDA |
|---|---|---|---|---|---|---|
| Q4-2025 | $17.24M ▲ | $73.71M ▲ | $-53.18M ▲ | -308.39% ▲ | $-0.3 ▲ | $-53.18M ▼ |
| Q3-2025 | $7.61M ▼ | $63.96M ▲ | $-53.85M ▼ | -707.83% ▼ | $-0.32 ▼ | $-51.62M ▼ |
| Q2-2025 | $8.7M ▼ | $59.26M ▲ | $-50.47M ▼ | -580.17% ▼ | $-0.31 ▼ | $-50.56M ▼ |
| Q1-2025 | $9.18M ▼ | $56.81M ▼ | $-46.88M ▼ | -510.93% ▼ | $-0.29 ▼ | $-47.64M ▼ |
| Q4-2024 | $83.75M | $60.78M | $29.25M | 34.93% | $0.18 | $25.12M |
Balance Statement
| Period | Cash & Short-term | Total Assets | Total Liabilities | Total Equity |
|---|---|---|---|---|
| Q4-2025 | $602.07M ▲ | $23.68M ▼ | $17.2M ▼ | $518.36M ▲ |
| Q3-2025 | $196.22M ▼ | $241.38M ▼ | $116.83M ▲ | $124.55M ▼ |
| Q2-2025 | $208.48M ▼ | $252.35M ▼ | $113.09M ▼ | $139.27M ▼ |
| Q1-2025 | $243.07M ▼ | $288.34M ▼ | $116.54M ▼ | $171.8M ▼ |
| Q4-2024 | $302.08M | $352.21M | $142.69M | $209.51M |
Cash Flow Statement
| Period | Net Income | Cash From Operations | Cash From Investing | Cash From Financing | Net Change | Free Cash Flow |
|---|---|---|---|---|---|---|
| Q4-2025 | $151.2M ▲ | $-33.78M ▲ | $1K ▲ | $439.69M ▲ | $0 ▲ | $-33.06M ▲ |
| Q3-2025 | $-53.85M ▼ | $-44.67M ▲ | $-248K ▲ | $32.69M ▲ | $-12.25M ▲ | $-44.91M ▲ |
| Q2-2025 | $-50.47M ▼ | $-46.01M ▲ | $-306K ▼ | $11.69M ▲ | $-34.58M ▲ | $-46.32M ▲ |
| Q1-2025 | $-46.88M ▼ | $-63.04M ▼ | $-165K ▼ | $4.16M ▼ | $-58.99M ▼ | $-63.2M ▼ |
| Q4-2024 | $29.25M | $-43.65M | $-86K | $34.98M | $-8.86M | $-43.73M |
Q4 2025 Earnings Call Summary
Read Call Summary5-Year Trend Analysis
A comprehensive look at Wave Life Sciences Ltd.'s financial evolution and strategic trajectory over the past five years.
Wave Life Sciences combines a strong scientific platform with a solid financial cushion. Its key strengths include a differentiated stereopure RNA technology, a versatile PRISM platform spanning multiple RNA modalities, and a pipeline featuring both rare disease and high‑impact common disease targets such as obesity. Financially, the company benefits from substantial cash reserves, minimal debt, and supportive partnerships that validate its approach and provide non‑product funding. This mix gives Wave time and flexibility to pursue its scientific goals.
The main risks center on sustained losses, ongoing cash burn, and high scientific and regulatory uncertainty. The business remains far from self‑funding and relies on capital markets and collaborators, exposing it to shifts in investor sentiment or partner priorities. Clinical setbacks, safety concerns, or regulatory delays in key programs like obesity, alpha‑1 antitrypsin deficiency, or Duchenne muscular dystrophy could significantly impair the platform’s perceived value. Accounting anomalies in non‑current assets and large accumulated losses also underscore the long and costly path the company has already traveled.
Looking ahead, Wave’s trajectory will be driven much more by clinical and partnership milestones than by near‑term financial metrics. The combination of strong liquidity and a focused, innovative pipeline gives it a window to prove out its technology. If upcoming data readouts and regulatory interactions are favorable, Wave could transition from a purely R&D‑driven story toward one with clearer commercial prospects. Conversely, a string of disappointments would magnify funding and strategic challenges. Overall, the outlook is high‑potential but high‑uncertainty, typical of a platform‑stage biotech company.
About Wave Life Sciences Ltd.
https://www.wavelifesciences.comWave Life Sciences Ltd., a clinical stage genetic medicine company, designs, optimizes, and produces novel stereopure oligonucleotides through PRISM, a discovery and drug developing platform. It is developing oligonucleotides target ribonucleic acid to reduce the expression of disease-promoting proteins or restore the production of functional proteins, or modulate protein expression.
Income Statement
| Period | Revenue | Operating Expense | Net Income | Net Profit Margin | Earnings Per Share | EBITDA |
|---|---|---|---|---|---|---|
| Q4-2025 | $17.24M ▲ | $73.71M ▲ | $-53.18M ▲ | -308.39% ▲ | $-0.3 ▲ | $-53.18M ▼ |
| Q3-2025 | $7.61M ▼ | $63.96M ▲ | $-53.85M ▼ | -707.83% ▼ | $-0.32 ▼ | $-51.62M ▼ |
| Q2-2025 | $8.7M ▼ | $59.26M ▲ | $-50.47M ▼ | -580.17% ▼ | $-0.31 ▼ | $-50.56M ▼ |
| Q1-2025 | $9.18M ▼ | $56.81M ▼ | $-46.88M ▼ | -510.93% ▼ | $-0.29 ▼ | $-47.64M ▼ |
| Q4-2024 | $83.75M | $60.78M | $29.25M | 34.93% | $0.18 | $25.12M |
Balance Statement
| Period | Cash & Short-term | Total Assets | Total Liabilities | Total Equity |
|---|---|---|---|---|
| Q4-2025 | $602.07M ▲ | $23.68M ▼ | $17.2M ▼ | $518.36M ▲ |
| Q3-2025 | $196.22M ▼ | $241.38M ▼ | $116.83M ▲ | $124.55M ▼ |
| Q2-2025 | $208.48M ▼ | $252.35M ▼ | $113.09M ▼ | $139.27M ▼ |
| Q1-2025 | $243.07M ▼ | $288.34M ▼ | $116.54M ▼ | $171.8M ▼ |
| Q4-2024 | $302.08M | $352.21M | $142.69M | $209.51M |
Cash Flow Statement
| Period | Net Income | Cash From Operations | Cash From Investing | Cash From Financing | Net Change | Free Cash Flow |
|---|---|---|---|---|---|---|
| Q4-2025 | $151.2M ▲ | $-33.78M ▲ | $1K ▲ | $439.69M ▲ | $0 ▲ | $-33.06M ▲ |
| Q3-2025 | $-53.85M ▼ | $-44.67M ▲ | $-248K ▲ | $32.69M ▲ | $-12.25M ▲ | $-44.91M ▲ |
| Q2-2025 | $-50.47M ▼ | $-46.01M ▲ | $-306K ▼ | $11.69M ▲ | $-34.58M ▲ | $-46.32M ▲ |
| Q1-2025 | $-46.88M ▼ | $-63.04M ▼ | $-165K ▼ | $4.16M ▼ | $-58.99M ▼ | $-63.2M ▼ |
| Q4-2024 | $29.25M | $-43.65M | $-86K | $34.98M | $-8.86M | $-43.73M |
Q4 2025 Earnings Call Summary
Read Call Summary5-Year Trend Analysis
A comprehensive look at Wave Life Sciences Ltd.'s financial evolution and strategic trajectory over the past five years.
Wave Life Sciences combines a strong scientific platform with a solid financial cushion. Its key strengths include a differentiated stereopure RNA technology, a versatile PRISM platform spanning multiple RNA modalities, and a pipeline featuring both rare disease and high‑impact common disease targets such as obesity. Financially, the company benefits from substantial cash reserves, minimal debt, and supportive partnerships that validate its approach and provide non‑product funding. This mix gives Wave time and flexibility to pursue its scientific goals.
The main risks center on sustained losses, ongoing cash burn, and high scientific and regulatory uncertainty. The business remains far from self‑funding and relies on capital markets and collaborators, exposing it to shifts in investor sentiment or partner priorities. Clinical setbacks, safety concerns, or regulatory delays in key programs like obesity, alpha‑1 antitrypsin deficiency, or Duchenne muscular dystrophy could significantly impair the platform’s perceived value. Accounting anomalies in non‑current assets and large accumulated losses also underscore the long and costly path the company has already traveled.
Looking ahead, Wave’s trajectory will be driven much more by clinical and partnership milestones than by near‑term financial metrics. The combination of strong liquidity and a focused, innovative pipeline gives it a window to prove out its technology. If upcoming data readouts and regulatory interactions are favorable, Wave could transition from a purely R&D‑driven story toward one with clearer commercial prospects. Conversely, a string of disappointments would magnify funding and strategic challenges. Overall, the outlook is high‑potential but high‑uncertainty, typical of a platform‑stage biotech company.

CEO
Paul B. Bolno
Compensation Summary
(Year 2024)
Upcoming Earnings
ETFs Holding This Stock
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Ratings Snapshot
Rating : C-
Most Recent Analyst Grades
Price Target
Institutional Ownership
GYON TECHNOLOGIES CAPITAL MANAGEMENT, LP
Shares:93.99M
Value:$1.31B
GSK PLC
Shares:18.25M
Value:$254.16M
RA CAPITAL MANAGEMENT, L.P.
Shares:18.2M
Value:$253.57M
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