XERS
XERS
Xeris Biopharma Holdings, Inc.Income Statement
| Period | Revenue | Operating Expense | Net Income | Net Profit Margin | Earnings Per Share | EBITDA |
|---|---|---|---|---|---|---|
| Q3-2025 | $74.38M ▲ | $56.65M ▲ | $621K ▲ | 0.83% ▲ | $0 ▲ | $11.08M ▲ |
| Q2-2025 | $71.54M ▲ | $52.45M ▼ | $-1.93M ▲ | -2.7% ▲ | $-0.01 ▲ | $8.59M ▲ |
| Q1-2025 | $60.12M ▲ | $54.48M ▲ | $-9.22M ▼ | -15.34% ▼ | $-0.06 ▼ | $1.23M ▼ |
| Q4-2024 | $60.1M ▲ | $48.94M ▼ | $-5.11M ▲ | -8.51% ▲ | $-0.03 ▲ | $5.72M ▲ |
| Q3-2024 | $54.27M | $53.57M | $-15.74M | -29% | $-0.11 | $-8.15M |
What's going well?
The company grew sales and significantly improved gross and operating margins. It swung from a loss to a profit, showing the core business is moving in the right direction.
What's concerning?
Operating expenses are rising faster than revenue, and heavy interest costs are eating into profits. Share dilution also reduces the benefit for existing shareholders.
Balance Statement
| Period | Cash & Short-term | Total Assets | Total Liabilities | Total Equity |
|---|---|---|---|---|
| Q3-2025 | $91.6M ▲ | $370.19M ▲ | $371.05M ▲ | $-861K ▲ |
| Q2-2025 | $59.28M ▲ | $334.69M ▲ | $353.99M ▲ | $-19.3M ▲ |
| Q1-2025 | $58.44M ▼ | $315.45M ▼ | $350.58M ▼ | $-35.13M ▼ |
| Q4-2024 | $71.62M ▲ | $323.06M ▲ | $352.68M ▲ | $-29.61M ▼ |
| Q3-2024 | $69.4M | $321.1M | $349.43M | $-28.32M |
What's financially strong about this company?
The company dramatically reduced its debt and now has a much stronger cash position. Liquidity is adequate, and most current bills can be paid with available assets.
What are the financial risks or weaknesses?
Shareholder equity is still negative, meaning the company owes more than it owns. Retained losses are huge, and future funding needs could lead to more share dilution or new debt.
Cash Flow Statement
| Period | Net Income | Cash From Operations | Cash From Investing | Cash From Financing | Net Change | Free Cash Flow |
|---|---|---|---|---|---|---|
| Q3-2025 | $621K ▲ | $18.43M ▲ | $-71K ▲ | $13.85M ▲ | $32.21M ▲ | $18.07M ▲ |
| Q2-2025 | $-1.93M ▲ | $182K ▲ | $-279K ▼ | $942K ▲ | $845K ▲ | $10.04M ▲ |
| Q1-2025 | $-9.22M ▼ | $-10.03M ▼ | $-13K ▼ | $-3.14M ▼ | $-13.18M ▼ | $-10.04M ▼ |
| Q4-2024 | $-5.11M ▲ | $1.98M ▲ | $10.02M ▲ | $398K ▲ | $12.39M ▲ | $1.75M ▲ |
| Q3-2024 | $-15.74M | $-8.3M | $9.91M | $-83K | $1.53M | $-8.39M |
What's strong about this company's cash flow?
XERS turned a small profit and generated much more cash from its business this quarter. Free cash flow nearly doubled, and the company now has a strong cash cushion.
What are the cash flow concerns?
Much of the cash boost came from working capital changes and issuing new shares, which dilutes existing shareholders. The big jump in cash flow may not repeat if working capital swings reverse.
Revenue by Products
| Product | Q4-2024 | Q1-2025 | Q2-2025 | Q3-2025 |
|---|---|---|---|---|
Keveyis | $20.00M ▲ | $10.00M ▼ | $10.00M ▲ | $10.00M ▲ |
Product | $100.00M ▲ | $60.00M ▼ | $70.00M ▲ | $70.00M ▲ |
Product Other | $0 ▲ | $0 ▲ | $0 ▲ | $0 ▲ |
Q3 2025 Earnings Call Summary
Read Call Summary5-Year Trend Analysis
A comprehensive look at Xeris Biopharma Holdings, Inc.'s financial evolution and strategic trajectory over the past five years.
Key positives include rapid and sustained revenue growth, very strong and improving gross margins, and a clear path of narrowing losses and lower cash burn. The company has carved out differentiated positions in specific endocrine and rare disease niches, supported by proprietary formulation technologies that improve convenience and patient experience. Strategic collaborations with major pharmaceutical partners further validate its platforms and offer additional, less capital‑intensive growth avenues.
The most significant concerns center on the balance sheet and capital structure: high and rising debt, negative equity, and a history of cumulative losses create meaningful financial risk. The business is still not generating positive free cash flow and remains dependent on external financing. Competitive and regulatory risks are also important, as Xeris faces larger, well‑funded rivals and must maintain favorable reimbursement and clinical positioning for its products to sustain growth.
If current trends continue—strong top‑line expansion, improving margins, and shrinking cash burn—Xeris appears to be progressing toward a more sustainable financial profile, with management commentary suggesting a line of sight to profitability on an adjusted basis. However, this positive operational trajectory must be weighed against its leveraged balance sheet and the need to execute well in competitive markets. Future performance will depend on maintaining commercial momentum in existing products, successfully advancing the pipeline (particularly XP‑8121), and carefully managing debt and liquidity to bridge the period until the business becomes consistently self‑funded.
About Xeris Biopharma Holdings, Inc.
https://www.xerispharma.comXeris Biopharma Holdings, Inc., a biopharmaceutical company, engages in developing and commercializing therapies for patient populations in endocrinology, neurology, and gastroenterology.
Income Statement
| Period | Revenue | Operating Expense | Net Income | Net Profit Margin | Earnings Per Share | EBITDA |
|---|---|---|---|---|---|---|
| Q3-2025 | $74.38M ▲ | $56.65M ▲ | $621K ▲ | 0.83% ▲ | $0 ▲ | $11.08M ▲ |
| Q2-2025 | $71.54M ▲ | $52.45M ▼ | $-1.93M ▲ | -2.7% ▲ | $-0.01 ▲ | $8.59M ▲ |
| Q1-2025 | $60.12M ▲ | $54.48M ▲ | $-9.22M ▼ | -15.34% ▼ | $-0.06 ▼ | $1.23M ▼ |
| Q4-2024 | $60.1M ▲ | $48.94M ▼ | $-5.11M ▲ | -8.51% ▲ | $-0.03 ▲ | $5.72M ▲ |
| Q3-2024 | $54.27M | $53.57M | $-15.74M | -29% | $-0.11 | $-8.15M |
What's going well?
The company grew sales and significantly improved gross and operating margins. It swung from a loss to a profit, showing the core business is moving in the right direction.
What's concerning?
Operating expenses are rising faster than revenue, and heavy interest costs are eating into profits. Share dilution also reduces the benefit for existing shareholders.
Balance Statement
| Period | Cash & Short-term | Total Assets | Total Liabilities | Total Equity |
|---|---|---|---|---|
| Q3-2025 | $91.6M ▲ | $370.19M ▲ | $371.05M ▲ | $-861K ▲ |
| Q2-2025 | $59.28M ▲ | $334.69M ▲ | $353.99M ▲ | $-19.3M ▲ |
| Q1-2025 | $58.44M ▼ | $315.45M ▼ | $350.58M ▼ | $-35.13M ▼ |
| Q4-2024 | $71.62M ▲ | $323.06M ▲ | $352.68M ▲ | $-29.61M ▼ |
| Q3-2024 | $69.4M | $321.1M | $349.43M | $-28.32M |
What's financially strong about this company?
The company dramatically reduced its debt and now has a much stronger cash position. Liquidity is adequate, and most current bills can be paid with available assets.
What are the financial risks or weaknesses?
Shareholder equity is still negative, meaning the company owes more than it owns. Retained losses are huge, and future funding needs could lead to more share dilution or new debt.
Cash Flow Statement
| Period | Net Income | Cash From Operations | Cash From Investing | Cash From Financing | Net Change | Free Cash Flow |
|---|---|---|---|---|---|---|
| Q3-2025 | $621K ▲ | $18.43M ▲ | $-71K ▲ | $13.85M ▲ | $32.21M ▲ | $18.07M ▲ |
| Q2-2025 | $-1.93M ▲ | $182K ▲ | $-279K ▼ | $942K ▲ | $845K ▲ | $10.04M ▲ |
| Q1-2025 | $-9.22M ▼ | $-10.03M ▼ | $-13K ▼ | $-3.14M ▼ | $-13.18M ▼ | $-10.04M ▼ |
| Q4-2024 | $-5.11M ▲ | $1.98M ▲ | $10.02M ▲ | $398K ▲ | $12.39M ▲ | $1.75M ▲ |
| Q3-2024 | $-15.74M | $-8.3M | $9.91M | $-83K | $1.53M | $-8.39M |
What's strong about this company's cash flow?
XERS turned a small profit and generated much more cash from its business this quarter. Free cash flow nearly doubled, and the company now has a strong cash cushion.
What are the cash flow concerns?
Much of the cash boost came from working capital changes and issuing new shares, which dilutes existing shareholders. The big jump in cash flow may not repeat if working capital swings reverse.
Revenue by Products
| Product | Q4-2024 | Q1-2025 | Q2-2025 | Q3-2025 |
|---|---|---|---|---|
Keveyis | $20.00M ▲ | $10.00M ▼ | $10.00M ▲ | $10.00M ▲ |
Product | $100.00M ▲ | $60.00M ▼ | $70.00M ▲ | $70.00M ▲ |
Product Other | $0 ▲ | $0 ▲ | $0 ▲ | $0 ▲ |
Q3 2025 Earnings Call Summary
Read Call Summary5-Year Trend Analysis
A comprehensive look at Xeris Biopharma Holdings, Inc.'s financial evolution and strategic trajectory over the past five years.
Key positives include rapid and sustained revenue growth, very strong and improving gross margins, and a clear path of narrowing losses and lower cash burn. The company has carved out differentiated positions in specific endocrine and rare disease niches, supported by proprietary formulation technologies that improve convenience and patient experience. Strategic collaborations with major pharmaceutical partners further validate its platforms and offer additional, less capital‑intensive growth avenues.
The most significant concerns center on the balance sheet and capital structure: high and rising debt, negative equity, and a history of cumulative losses create meaningful financial risk. The business is still not generating positive free cash flow and remains dependent on external financing. Competitive and regulatory risks are also important, as Xeris faces larger, well‑funded rivals and must maintain favorable reimbursement and clinical positioning for its products to sustain growth.
If current trends continue—strong top‑line expansion, improving margins, and shrinking cash burn—Xeris appears to be progressing toward a more sustainable financial profile, with management commentary suggesting a line of sight to profitability on an adjusted basis. However, this positive operational trajectory must be weighed against its leveraged balance sheet and the need to execute well in competitive markets. Future performance will depend on maintaining commercial momentum in existing products, successfully advancing the pipeline (particularly XP‑8121), and carefully managing debt and liquidity to bridge the period until the business becomes consistently self‑funded.

CEO
John P. Shannon
Compensation Summary
(Year 2024)
Upcoming Earnings
ETFs Holding This Stock
Summary
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Ratings Snapshot
Rating : C
Most Recent Analyst Grades
HC Wainwright & Co.
Buy
Oppenheimer
Outperform
Piper Sandler
Neutral
Leerink Partners
Outperform
Craig-Hallum
Buy
Grade Summary
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Price Target
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