XERS - Xeris Biopharma Hol... Stock Analysis | Stock Taper
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Xeris Biopharma Holdings, Inc.

XERS

Xeris Biopharma Holdings, Inc. NASDAQ
$6.17 -0.52% (-0.03)

Market Cap $1.07 B
52w High $10.08
52w Low $3.95
P/E -61.68
Volume 1.02M
Outstanding Shares 172.43M

Income Statement

Period Revenue Operating Expense Net Income Net Profit Margin Earnings Per Share EBITDA
Q4-2025 $85.81M $49.95M $11.08M 12.91% $0.07 $14.13M
Q3-2025 $74.38M $56.65M $621K 0.83% $0 $11.08M
Q2-2025 $71.54M $52.45M $-1.93M -2.7% $-0.01 $8.59M
Q1-2025 $60.12M $54.48M $-9.22M -15.34% $-0.06 $1.23M
Q4-2024 $60.1M $48.94M $-5.11M -8.51% $-0.03 $5.72M

Balance Statement

Period Cash & Short-term Total Assets Total Liabilities Total Equity
Q4-2025 $111.04M $383.53M $369.84M $13.69M
Q3-2025 $91.6M $370.19M $371.05M $-861K
Q2-2025 $59.28M $334.69M $353.99M $-19.3M
Q1-2025 $58.44M $315.45M $350.58M $-35.13M
Q4-2024 $71.62M $323.06M $352.68M $-29.61M

Cash Flow Statement

Period Net Income Cash From Operations Cash From Investing Cash From Financing Net Change Free Cash Flow
Q4-2025 $11.08M $20.04M $-333K $-266K $19.44M $19.71M
Q3-2025 $621K $18.43M $-71K $13.85M $32.21M $18.07M
Q2-2025 $-1.93M $182K $-279K $942K $845K $10.04M
Q1-2025 $-9.22M $-10.03M $-13K $-3.14M $-13.18M $-10.04M
Q4-2024 $-5.11M $1.98M $10.02M $398K $12.39M $1.75M

Revenue by Products

Product Q1-2025Q2-2025Q3-2025Q4-2025
Keveyis
Keveyis
$10.00M $10.00M $10.00M $10.00M
Product
Product
$60.00M $70.00M $70.00M $80.00M
Product Other
Product Other
$0 $0 $0 $0

Q4 2025 Earnings Call Summary

Read Call Summary

5-Year Trend Analysis

A comprehensive look at Xeris Biopharma Holdings, Inc.'s financial evolution and strategic trajectory over the past five years.

+ Strengths

Key strengths include a growing commercial revenue base, a recent transition to positive profitability and cash generation, and a strong short‑term liquidity position with net cash. Technologically, the company benefits from differentiated formulation platforms, a protected patent estate, and a track record of converting that technology into approved, patient‑friendly products. Its focused presence in endocrine and rare disease markets, supported by strategic partnerships, provides a clear strategic identity rather than a scattered portfolio.

! Risks

Major risks stem from the narrow product base, high dependence on a few therapies, and the inherently uncertain nature of drug development and regulatory approvals. The balance sheet shows significant accumulated losses and a high proportion of intangible assets, which reduce the buffer against adverse events. Operating leverage cuts both ways: high fixed commercial and overhead costs mean that any slowdown in revenue growth could quickly pressure margins and cash flow. Competition, pricing pressure, potential generic entry, and execution risk around XP‑8121 and other pipeline assets add further uncertainty.

Outlook

The outlook is cautiously constructive: Xeris has demonstrated that its business model can produce revenue growth, operating profits, and free cash flow, while its technology platforms and pipeline offer avenues for further expansion. Management’s expectations for continued strong top‑line growth underscore the potential, but outcomes will hinge on successful scaling of existing products, disciplined cost control, and the clinical and commercial success of XP‑8121 and future partnered programs. Overall, the company appears to be moving from a proof‑of‑concept stage toward a more established specialty‑pharma profile, though execution and external risks remain meaningful and should be monitored closely.