Stock Taper 
SIREN, L.L.C.
Latest 13F filing data - Q2 2026
Holdings
(Top positions)| STOCK | TICKER | SHARES HELD▲ ▼ | VALUE▲ ▼ |
|---|---|---|---|
 Cogent Biosciences, Inc. | COGT | 1.86M | $71.95M |
 Trevi Therapeutics, Inc. | TRVI | 1.79M | $33.33M |
 Enliven Therapeutics, Inc. | ELVN | 1.77M | $90.05M |
 Arrowhead Pharmaceuticals, Inc. | ARWR | 1.72M | $139.83M |
 Veradermics, Incorporated | MANE | 1.66M | $203.51M |
 Remitly Global, Inc. | RELY | 1.54M | $34.58M |
 Amylyx Pharmaceuticals, Inc. | AMLX | 1.48M | $26.59M |
 Crinetics Pharmaceuticals, Inc. | CRNX | 1.42M | $53.17M |
 Definium Therapeutics, Inc. | DFTX | 1.42M | $66.77M |
 Denali Therapeutics Inc. | DNLI | 1.4M | $35.92M |
 Xenon Pharmaceuticals Inc. | XENE | 1.32M | $79.59M |
 Rhythm Pharmaceuticals, Inc. | RYTM | 1.14M | $126.16M |
 Seaport Therapeutics, Inc. Common Stock | SPTX | 1.1M | $23.79M |
 Agenus Inc. | AGEN | 1.06M | $3.26M |
 Spyre Therapeutics, Inc. | SYRE | 968.6K | $85.99M |
 Revolution Medicines, Inc. | RVMD | 900K | $168.55M |
 Disc Medicine, Inc. | IRON | 888.4K | $64.98M |
 Cytokinetics, Incorporated | CYTK | 758.95K | $64.66M |
 Tyra Biosciences, Inc. | TYRA | 725K | $23.16M |
 Rapport Therapeutics, Inc. Common Stock | RAPP | 641.47K | $26.73M |