CTMX - CytomX Therapeutics... Stock Analysis | Stock Taper
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CytomX Therapeutics, Inc.

CTMX

CytomX Therapeutics, Inc. NASDAQ
$4.82 -1.43% (-0.07)

Market Cap $820.61 M
52w High $8.21
52w Low $0.63
P/E -32.13
Volume 4.92M
Outstanding Shares 170.25M

Income Statement

Period Revenue Operating Expense Net Income Net Profit Margin Earnings Per Share EBITDA
Q4-2025 $663K $28.09M $-26.51M -4K% $-0.17 $-27.42M
Q3-2025 $5.96M $21.73M $-14.23M -238.62% $-0.09 $-14.04M
Q2-2025 $18.66M $19.94M $-154K -0.83% $-0 $-939K
Q1-2025 $50.92M $28.3M $23.52M 46.2% $0.27 $23.01M
Q4-2024 $38.09M $20.41M $18.88M 49.55% $0.24 $18.09M

Balance Statement

Period Cash & Short-term Total Assets Total Liabilities Total Equity
Q4-2025 $137.05M $152.5M $52.56M $99.01M
Q3-2025 $143.63M $158.25M $50.87M $107.39M
Q2-2025 $158.09M $175.06M $55.15M $119.91M
Q1-2025 $79.89M $98.5M $73.45M $25.05M
Q4-2024 $100.62M $120.53M $120.99M $-456K

Cash Flow Statement

Period Net Income Cash From Operations Cash From Investing Cash From Financing Net Change Free Cash Flow
Q4-2025 $-26.51M $-23.24M $-14.42M $16.64M $-21.02M $-23.44M
Q3-2025 $-14.23M $-15.55M $439K $253K $-14.86M $-15.42M
Q2-2025 $-154K $-15.75M $-76.36M $93.55M $1.44M $-15.78M
Q1-2025 $23.52M $-21.04M $30.6M $0 $9.55M $-21.16M
Q4-2024 $18.88M $-19.91M $15.13M $2.25M $-2.52M $-19.99M

Q4 2025 Earnings Call Summary

Read Call Summary

5-Year Trend Analysis

A comprehensive look at CytomX Therapeutics, Inc.'s financial evolution and strategic trajectory over the past five years.

+ Strengths

CTMX combines a differentiated scientific platform with a reasonably strong financial foundation for a clinical‑stage biotech. Its PROBODY technology offers a clear, intuitive rationale for better targeting of cancer therapies, and early data from its lead ADC support that promise. The company has attracted collaborations with major pharmaceutical players, which both validate the science and provide non‑dilutive funding opportunities. On the financial side, it holds substantial cash and short‑term investments, carries little debt, and appears to have a defined operating runway, giving it time to pursue its clinical objectives.

! Risks

The main risks are classic for this stage of biotech: persistent operating losses, heavy cash burn, and a long history of cumulative deficits. The business is entirely dependent on the success of a limited number of clinical programs and on navigating regulatory hurdles in complex, crowded oncology indications. Any disappointing trial results, safety findings, or regulatory delays could significantly undermine the company’s prospects. Competition from larger, well‑funded companies is intense, and continued reliance on equity and partnership financing introduces dilution and counterparty risks, especially beyond the current runway.

Outlook

The outlook for CTMX is highly binary and driven more by science and clinical execution than by current financial performance. If the lead ADC progresses smoothly into and through registrational trials and the broader PROBODY platform continues to generate positive data, the company could transition from an early‑stage innovator into a more established oncology player with substantial partnering and commercialization opportunities. If key programs stumble, the strong balance sheet buys only limited time, and the company may need to rethink its strategy or structure. Overall, CTMX is best viewed as a high‑risk, high‑uncertainty development story where upcoming clinical milestones and partnership dynamics will be far more important than near‑term earnings or revenue trends.