CTMX
CTMX
CytomX Therapeutics, Inc.Income Statement
| Period | Revenue | Operating Expense | Net Income | Net Profit Margin | Earnings Per Share | EBITDA |
|---|---|---|---|---|---|---|
| Q4-2025 | $663K ▼ | $28.09M ▲ | $-26.51M ▼ | -4K% ▼ | $-0.17 ▼ | $-27.42M ▼ |
| Q3-2025 | $5.96M ▼ | $21.73M ▲ | $-14.23M ▼ | -238.62% ▼ | $-0.09 ▼ | $-14.04M ▼ |
| Q2-2025 | $18.66M ▼ | $19.94M ▼ | $-154K ▼ | -0.83% ▼ | $-0 ▼ | $-939K ▼ |
| Q1-2025 | $50.92M ▲ | $28.3M ▲ | $23.52M ▲ | 46.2% ▼ | $0.27 ▲ | $23.01M ▲ |
| Q4-2024 | $38.09M | $20.41M | $18.88M | 49.55% | $0.24 | $18.09M |
Balance Statement
| Period | Cash & Short-term | Total Assets | Total Liabilities | Total Equity |
|---|---|---|---|---|
| Q4-2025 | $137.05M ▼ | $152.5M ▼ | $52.56M ▲ | $99.01M ▼ |
| Q3-2025 | $143.63M ▼ | $158.25M ▼ | $50.87M ▼ | $107.39M ▼ |
| Q2-2025 | $158.09M ▲ | $175.06M ▲ | $55.15M ▼ | $119.91M ▲ |
| Q1-2025 | $79.89M ▼ | $98.5M ▼ | $73.45M ▼ | $25.05M ▲ |
| Q4-2024 | $100.62M | $120.53M | $120.99M | $-456K |
Cash Flow Statement
| Period | Net Income | Cash From Operations | Cash From Investing | Cash From Financing | Net Change | Free Cash Flow |
|---|---|---|---|---|---|---|
| Q4-2025 | $-26.51M ▼ | $-23.24M ▼ | $-14.42M ▼ | $16.64M ▲ | $-21.02M ▼ | $-23.44M ▼ |
| Q3-2025 | $-14.23M ▼ | $-15.55M ▲ | $439K ▲ | $253K ▼ | $-14.86M ▼ | $-15.42M ▲ |
| Q2-2025 | $-154K ▼ | $-15.75M ▲ | $-76.36M ▼ | $93.55M ▲ | $1.44M ▼ | $-15.78M ▲ |
| Q1-2025 | $23.52M ▲ | $-21.04M ▼ | $30.6M ▲ | $0 ▼ | $9.55M ▲ | $-21.16M ▼ |
| Q4-2024 | $18.88M | $-19.91M | $15.13M | $2.25M | $-2.52M | $-19.99M |
Q4 2025 Earnings Call Summary
Read Call Summary5-Year Trend Analysis
A comprehensive look at CytomX Therapeutics, Inc.'s financial evolution and strategic trajectory over the past five years.
CTMX combines a differentiated scientific platform with a reasonably strong financial foundation for a clinical‑stage biotech. Its PROBODY technology offers a clear, intuitive rationale for better targeting of cancer therapies, and early data from its lead ADC support that promise. The company has attracted collaborations with major pharmaceutical players, which both validate the science and provide non‑dilutive funding opportunities. On the financial side, it holds substantial cash and short‑term investments, carries little debt, and appears to have a defined operating runway, giving it time to pursue its clinical objectives.
The main risks are classic for this stage of biotech: persistent operating losses, heavy cash burn, and a long history of cumulative deficits. The business is entirely dependent on the success of a limited number of clinical programs and on navigating regulatory hurdles in complex, crowded oncology indications. Any disappointing trial results, safety findings, or regulatory delays could significantly undermine the company’s prospects. Competition from larger, well‑funded companies is intense, and continued reliance on equity and partnership financing introduces dilution and counterparty risks, especially beyond the current runway.
The outlook for CTMX is highly binary and driven more by science and clinical execution than by current financial performance. If the lead ADC progresses smoothly into and through registrational trials and the broader PROBODY platform continues to generate positive data, the company could transition from an early‑stage innovator into a more established oncology player with substantial partnering and commercialization opportunities. If key programs stumble, the strong balance sheet buys only limited time, and the company may need to rethink its strategy or structure. Overall, CTMX is best viewed as a high‑risk, high‑uncertainty development story where upcoming clinical milestones and partnership dynamics will be far more important than near‑term earnings or revenue trends.
About CytomX Therapeutics, Inc.
https://www.cytomx.comCytomX Therapeutics, Inc. operates as an oncology-focused biopharmaceutical company in the United States. The company develops antibody therapeutics based on its Probody technology platform for the treatment of cancer.
Income Statement
| Period | Revenue | Operating Expense | Net Income | Net Profit Margin | Earnings Per Share | EBITDA |
|---|---|---|---|---|---|---|
| Q4-2025 | $663K ▼ | $28.09M ▲ | $-26.51M ▼ | -4K% ▼ | $-0.17 ▼ | $-27.42M ▼ |
| Q3-2025 | $5.96M ▼ | $21.73M ▲ | $-14.23M ▼ | -238.62% ▼ | $-0.09 ▼ | $-14.04M ▼ |
| Q2-2025 | $18.66M ▼ | $19.94M ▼ | $-154K ▼ | -0.83% ▼ | $-0 ▼ | $-939K ▼ |
| Q1-2025 | $50.92M ▲ | $28.3M ▲ | $23.52M ▲ | 46.2% ▼ | $0.27 ▲ | $23.01M ▲ |
| Q4-2024 | $38.09M | $20.41M | $18.88M | 49.55% | $0.24 | $18.09M |
Balance Statement
| Period | Cash & Short-term | Total Assets | Total Liabilities | Total Equity |
|---|---|---|---|---|
| Q4-2025 | $137.05M ▼ | $152.5M ▼ | $52.56M ▲ | $99.01M ▼ |
| Q3-2025 | $143.63M ▼ | $158.25M ▼ | $50.87M ▼ | $107.39M ▼ |
| Q2-2025 | $158.09M ▲ | $175.06M ▲ | $55.15M ▼ | $119.91M ▲ |
| Q1-2025 | $79.89M ▼ | $98.5M ▼ | $73.45M ▼ | $25.05M ▲ |
| Q4-2024 | $100.62M | $120.53M | $120.99M | $-456K |
Cash Flow Statement
| Period | Net Income | Cash From Operations | Cash From Investing | Cash From Financing | Net Change | Free Cash Flow |
|---|---|---|---|---|---|---|
| Q4-2025 | $-26.51M ▼ | $-23.24M ▼ | $-14.42M ▼ | $16.64M ▲ | $-21.02M ▼ | $-23.44M ▼ |
| Q3-2025 | $-14.23M ▼ | $-15.55M ▲ | $439K ▲ | $253K ▼ | $-14.86M ▼ | $-15.42M ▲ |
| Q2-2025 | $-154K ▼ | $-15.75M ▲ | $-76.36M ▼ | $93.55M ▲ | $1.44M ▼ | $-15.78M ▲ |
| Q1-2025 | $23.52M ▲ | $-21.04M ▼ | $30.6M ▲ | $0 ▼ | $9.55M ▲ | $-21.16M ▼ |
| Q4-2024 | $18.88M | $-19.91M | $15.13M | $2.25M | $-2.52M | $-19.99M |
Q4 2025 Earnings Call Summary
Read Call Summary5-Year Trend Analysis
A comprehensive look at CytomX Therapeutics, Inc.'s financial evolution and strategic trajectory over the past five years.
CTMX combines a differentiated scientific platform with a reasonably strong financial foundation for a clinical‑stage biotech. Its PROBODY technology offers a clear, intuitive rationale for better targeting of cancer therapies, and early data from its lead ADC support that promise. The company has attracted collaborations with major pharmaceutical players, which both validate the science and provide non‑dilutive funding opportunities. On the financial side, it holds substantial cash and short‑term investments, carries little debt, and appears to have a defined operating runway, giving it time to pursue its clinical objectives.
The main risks are classic for this stage of biotech: persistent operating losses, heavy cash burn, and a long history of cumulative deficits. The business is entirely dependent on the success of a limited number of clinical programs and on navigating regulatory hurdles in complex, crowded oncology indications. Any disappointing trial results, safety findings, or regulatory delays could significantly undermine the company’s prospects. Competition from larger, well‑funded companies is intense, and continued reliance on equity and partnership financing introduces dilution and counterparty risks, especially beyond the current runway.
The outlook for CTMX is highly binary and driven more by science and clinical execution than by current financial performance. If the lead ADC progresses smoothly into and through registrational trials and the broader PROBODY platform continues to generate positive data, the company could transition from an early‑stage innovator into a more established oncology player with substantial partnering and commercialization opportunities. If key programs stumble, the strong balance sheet buys only limited time, and the company may need to rethink its strategy or structure. Overall, CTMX is best viewed as a high‑risk, high‑uncertainty development story where upcoming clinical milestones and partnership dynamics will be far more important than near‑term earnings or revenue trends.

CEO
Sean A. McCarthy
Compensation Summary
(Year 2024)
Upcoming Earnings
ETFs Holding This Stock
Summary
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Ratings Snapshot
Rating : D+
Most Recent Analyst Grades
Price Target
Institutional Ownership
FMR LLC
Shares:24.69M
Value:$119M
VR ADVISER, LLC
Shares:15.56M
Value:$75.01M
TANG CAPITAL MANAGEMENT LLC
Shares:11.07M
Value:$53.34M
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