SIREN, L.L.C.
Latest 13F filing data - Q3 2025
Holdings (Top positions)
| Stock | Ticker | ||
|---|---|---|---|
 | APLS | 2.58M | $58.35M |
 | TRVI | 2.54M | $23.21M |
 | IHS | 2.36M | $16.08M |
 | STOK | 2.25M | $52.81M |
 | SEPN | 2.20M | $41.43M |
 | ELDN | 2.07M | $5.37M |
 | BCYC | 2.01M | $15.58M |
 | COGT | 1.72M | $24.76M |
 | CRNX | 1.69M | $70.33M |
 | RELY | 1.62M | $26.38M |
 | PRQR | 1.55M | $3.31M |
 | RNA | 1.29M | $56.01M |
 | CGEM | 1.19M | $7.08M |
 | IMAB | 1.17M | $4.41M |
 | AGEN | 1.06M | $4.10M |
 | RAPP | 1.05M | $31.29M |
 | BDTX | 1.05M | $3.97M |
 | RVMD | 1.04M | $48.74M |
 | GPCR | 1.03M | $28.75M |
 | ORIC | 1.01M | $12.09M |
Apellis Pharmaceuticals, Inc.
APLS
Shares Held
2.58M
Value
$58.35M
Trevi Therapeutics, Inc.
TRVI
Shares Held
2.54M
Value
$23.21M
IHS Holding Limited
IHS
Shares Held
2.36M
Value
$16.08M
Stoke Therapeutics, Inc.
STOK
Shares Held
2.25M
Value
$52.81M
Septerna, Inc.
SEPN
Shares Held
2.20M
Value
$41.43M
Eledon Pharmaceuticals, Inc.
ELDN
Shares Held
2.07M
Value
$5.37M
Bicycle Therapeutics plc
BCYC
Shares Held
2.01M
Value
$15.58M
Cogent Biosciences, Inc.
COGT
Shares Held
1.72M
Value
$24.76M
Crinetics Pharmaceuticals, Inc.
CRNX
Shares Held
1.69M
Value
$70.33M
Remitly Global, Inc.
RELY
Shares Held
1.62M
Value
$26.38M
ProQR Therapeutics N.V.
PRQR
Shares Held
1.55M
Value
$3.31M
Avidity Biosciences, Inc.
RNA
Shares Held
1.29M
Value
$56.01M
Cullinan Therapeutics, Inc.
CGEM
Shares Held
1.19M
Value
$7.08M
I-Mab
IMAB
Shares Held
1.17M
Value
$4.41M
Agenus Inc.
AGEN
Shares Held
1.06M
Value
$4.10M
Rapport Therapeutics, Inc. Common Stock
RAPP
Shares Held
1.05M
Value
$31.29M
Black Diamond Therapeutics, Inc.
BDTX
Shares Held
1.05M
Value
$3.97M
Revolution Medicines, Inc.
RVMD
Shares Held
1.04M
Value
$48.74M
Structure Therapeutics Inc.
GPCR
Shares Held
1.03M
Value
$28.75M
ORIC Pharmaceuticals, Inc.
ORIC
Shares Held
1.01M
Value
$12.09M